Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID08170 Jnk-9l GSE70138 HA1E Human 24h 10uM EID0010
Types Number Response transcription factors
Up-regulation 641 ZNF264; EGR1; ZNF695; SOX5; SCAI; ZNF551; ZNF224; ZNF154; CARF; OVOL2; ZNF391; CHD2; FEZF2; ZNF688; CEBPD; FOSB; ASCL3; ZNF701; PRDM14; ZNF816; ZKSCAN8; SRY; NR4A2; RFX3; MAML3; SSX7; ZNF304; RFX1; HIPK2; MAK; ALX4; KAT2B; NEUROD4; TBR1; ZNF345; SOX21; FOXE3; ZNF606; ZNF235; POU6F2; SHOX; ZNF682; PRDM2; TP73; VGLL1; MYCL; NHLH2; ZNF749; SP4; ZNF257; ZNF221; FOS; IKZF2; ZNF778; ZNF549; ZFPM2; FOXD3; NKX3-2; NEUROG2; ZKSCAN4; ZNF362; ZNF440; TWIST1; NR5A2; DOT1L; MYT1; ZFHX2; PRDM9; HOXB8; ATF7; CIITA; ESR2; SIX6; ZNF208; POU2F3; IRF6; ZIC3; HOXD3; RBPJL; ZNF471; ZNF223; VENTX; ZXDC; ZNF492; ZNF75D; SPI1; TEF; GBX1; ONECUT1; ZNF124; HESX1; NEUROD2; SOX1; PRDM16; HNF4G; ZNF814; ZNF667; ZNF343; TBX6; THRB; BCL11A; ATOH1; ZNF136; KLF8; L3MBTL1; AR; ZNF141; TULP1; BRDT; SCRT1; HES2; ZNF835; SOX17; KMT2D; ZNF780B; SOX18; ZNF674; ZFP2; ZNF544; ZFY; LHX6; ZNF80; HIF3A; EMX1; ZNF225; HEYL; ZNF157; MDM4; NFKB2; SOX14; ZNF132; CBX7; ZSCAN2; HOXA2; ZIC4; PROP1; ZNF117; PDX1; ZNF407; PAX4; VHL; ZNF493; PPARA; KDM5A; GRIP1; ZNF234; ERBB4; ZBTB7C; PRDM10; LHX3; POU4F2; GCM2; TBX19; ZNF550; ZIM2; ZNF334; SSX3; NR6A1; HNF4A; ATF6B; GSC2; ZNF254; ZNF81; MYEF2; PAX7; ESRRB; ONECUT2; ZNF10; SUPT3H; ZNF467; TAF4B; POU1F1; PRDM5; ZNF180; RSF1; ZNF484; TULP2; UTF1; DCC; FOXB1; NACA2; ZNF623; ZNF442; HAND1; ZNF214; CDX4; ZNF219; ZNF611; NEUROD6; CREBL2; ZNF528; TLX3; PAX6; TCEA2; ZNF507; TBX5; MAPK8IP1; RNF2; ZNF155; NR5A1; HIVEP3; ZNF273; EPAS1; THAP9; TFDP3; FHL5; HOXA3; WHSC1L1; ZNF669; HOXD12; MLLT1; TLX1; TBX1; SOX30; SOX3; NEUROG3; NKX6-1; THRA; IKZF3; CRX; ARID3A; HSF4; POU3F3; HOXB1; ZNF8; RARG; NKX2-8; NFATC4; ZNF287; MEOX2; GBX2; ZNF573; AIRE; TBL1Y; PAX3; ARHGAP35; NR4A3; WNT4; ST18; NEUROG1; MSX2; ZNF460; FOXD2; ZNF480; TLX2; NR4A1; NFIX; POU4F3; HNF1A; CUX2; EGR4; FOSL1; NR1H4; PRDM13; LBX1; ETV3; ATF3; SOHLH2; ZNF711; HDAC5; RFX2; NR2E1; FOXA1; ZSCAN9; ZNF771; ZNF41; FOXN1; OVOL1; ZNF135; MNX1; ZBTB3; POU2F1; FOXL1; FOXH1; RUNX2; MDM2; E2F4; ZNF33B; RORC; EP300; HAND2; HMGA2; ASCL2; GCM1; GCFC2; CD3D; HOXC5; ZNF197; GRHL2; VSX1; SKIL; CREM; LIN28A; ING4; TAL1; ASH1L; ETV2; ZNF358; NOCT; BARX1; NEUROD1; RORB; NFAT5; SRCAP; ZBTB20; MECP2; SALL2; CBFA2T3; REL; ZNF44; ZNF274; ACTL6B; POU3F4; ZNF764; ZNF142; MYCBP; HDAC11; ZNF93; ZNF529; TONSL; ZFP69B; ZNF552; ZNF211; CBX8; CBX2; SIX3; NKX2-5; TTF2; CEBPE; MECOM; PAX1; FOXJ1; TAF1C; FOXJ2; TBX10; MNDA; TUB; ZNF174; TAF6L; SKI; ZNF613; NHLH1; ZNF665; ESRRG; BNC1; DLX6; ZNF671; ZNF710; HOXB5; CBX4; ZNF556; HOXC8; ZNF14; SIX5; DBP; ZNF423; BNC2; SUV39H2; SLC2A4RG; GTF2A1; NPAS1; ALX3; ZNF329; NFX1; ZNF331; TBX4; AFF2; AFF3; ZSCAN31; CDX1; ZNF675; CERS6; ZKSCAN7; IRF1; FOXO4; POU6F1; DMRT1; PRDM12; TAF7L; ZNF286A; KLF3; TSHZ2; RBL2; NR1I3; INSM1; TFEC; EHMT2; HNF1B; ZNF500; STAT2; ZNF415; ZNF215; ESR1; HIC1; ZKSCAN3; ZNF107; ZNF226; MYT1L; SPDEF; NFKBIB; MYNN; CREG1; ZBTB6; ZNF557; BRWD1; YBX2; LHX5; ZNF419; NR0B2; EBF2; ATN1; AEBP1; POU3F2; FOXG1; TCF21; LMX1B; ZNF253; DLX5; KLF15; SNAI1; MXD4; MAP3K10; HOXD13; MED31; ZBTB44; ZNF770; TFAP2B; ZXDB; TFDP2; EYA3; E2F1; ZNF506; GFI1; RXRG; ZNF76; FOXN2; ZFP37; HLF; PAX9; TFAP2A; PLAGL1; ARNT; MAFK; BHLHE40; AFF4; RAX; ZBTB39; MEIS2; MZF1; SMAD5; CDIP1; SHOX2; PRDM1; PEG3; HBP1; RORA; PBX1; GATA3; EN1; LDB1; ZNF3; ZBTB32; FOXC2; ZNF43; POU5F1B; CAMTA2; ZNF536; ZNF350; MBD4; MED14; ZNF222; HOXD1; LZTR1; MXI1; ZNF74; EMX2; EN2; MAFF; ZNF236; FOXP3; MED25; TAF1; DLX4; FOXL2; ZFHX3; ZBTB7B; PBX2; ZNF85; HEY2; ZBTB48; PIR; NR1I2; ZNF571; INSR; HIC2; BCL6; HDAC9; ZNF184; PKNOX2; ZNF112; CIR1; IRF4; FOXF1; ZBED2; ARNT2; MKL1; SP140; TBX21; CSDC2; KLF13; THAP10; ZKSCAN1; AES; PRRX1; SSBP3; CREB5; FOXA2; IRF8; GLI2; SOX13; NANOG; MTA2; SCMH1; TGFB1; PNRC1; PEX2; ZNF468; ZNF205; LHX2; HMGA1; PRMT2; PITX1; ZNF426; TAF6; RING1; CNBP; CBX6; ELK4; HIPK3; NKX2-2; ZNF562; ZNF160; ING1; ZNF175; BAZ2A; KLF7; NR1D2; GATA1; LZTS1; HEY1; ZNF587; ZNF91; ZNF354A; EGR2; MTA1; HHEX; PHOX2A; KDM4C; CERS4; WWTR1; SAP18; HMBOX1; PROX1; NKX2-1; NR0B1; ZNF83; ZNF652; ETV5; PHOX2B; SMAD6; GFI1B; TCEB2; ZNF721; WT1; RNF141; TCF4; KLF11; MEF2C; SSX1; PLAG1; FLI1; SPIB; CNOT2; LYL1; ZNF165; HIPK1; SOX11; EGR3; CREB3L2; MSX1; FOXF2; STAT4; SP140L; NFIC; TRIB3; HLX; NFE2L3; CSDE1; CNOT3; KLF4; ELF3; RUNX3; TULP3; LEF1; LITAF; ZIC1; DLX2; ZNF532; ARNTL2; E2F5; ISL1; E2F2; WWP1; NR1H3; HLTF; CALR; TOX; GTF3A; RBFOX2; MYCN; NR1H2; EYA1; SMARCA1; MYRF; IKZF1; TCF7; NCOA3; CRYM; ZNF589; EHF; MAFB; ID1; CARHSP1; SOX2; MEIS1; GATA6; OSR2; AHR; TXNIP; ID3; GATA2
Down-regulation 187 CCNA2; PUF60; SUV39H1; FOXO3; XBP1; ECD; NUP62; TCERG1; PAX8; FHL2; HNRNPD; SNW1; USP22; CENPF; TLE1; SMARCA5; ARID5B; UBE2I; NFIL3; HDAC2; VEZF1; RBM14; TP53; GTF2A2; CRK; RNF111; TRIM32; SFPQ; ATF6; SMAD3; HMGB2; BRD3; AATF; TAF9; DEK; BCLAF1; EED; MED27; CDK2; HOXA10; CDK7; ATF1; DNAJC2; ERBB2; BRD8; ZNF146; RBM39; ZNF263; NCOA6; ING2; YWHAB; NRIP1; CRY1; KAT7; ITGB3BP; NFE2L1; DDX5; NPAT; FOXK2; PCGF2; NCOA4; EDF1; TRIM29; MED13; BMI1; HOXC6; NELFB; BAZ1A; ZBTB1; TRIM27; KAT6A; TBL1X; PRPF6; MAX; ZNF410; MLX; HOXA5; RAN; TAF7; ELF1; MED6; CEBPZ; PPRC1; AFF1; SF1; PATZ1; ZMYM2; SMARCE1; ARID4B; EZH2; JARID2; RBBP4; HMG20A; GTF2IRD1; CTR9; PTTG1; BLM; ASXL1; ADNP; SMARCD3; RNF138; NCOR1; MBD2; PREB; CNOT6; ELF5; SOX9; RBPJ; SUZ12; REST; CCNC; NFIB; NFKB1; PHF20; COPS5; CNOT1; MED1; SAP30; STAT3; ZNF281; MTF2; RCOR1; FOXC1; HOXC10; SETD2; ASH2L; CTCF; TAF4; HMGB1; ZNF266; MYBL1; BRCA1; TBL1XR1; HDAC7; CCDC59; ENO1; NKX3-1; KLF6; HIF1A; MAGED1; IKBKAP; NPM1; GATAD2A; NFYB; PQBP1; FLNA; CTBP2; RAD21; SMAD4; MLXIP; SCAND1; PSPC1; FOXJ3; RNF6; HOXA11; SMAD7; CBX3; ZMIZ1; ZBTB11; VDR; ID2; TCF12; STAT6; TBX3; NRBF2; CBFB; REPIN1; CHD1; NR2F2; RBPMS; MED21; MED24; ILF2; SMAD1; ELK3; FOSL2; ID4; SIAH2; KLF10; ZBTB18; RUNX1; CHD7; RBBP8; PBX3; ABL1; NR3C1; RELB