Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID08163 Azd-5438 GSE70138 HA1E Human 24h 0.04uM EID0010
Types Number Response transcription factors
Up-regulation 80 EGR2; MYBL2; ZNF274; SIAH2; ZNF195; TFEB; NRBF2; TCF3; HABP4; MMS19; PAX9; SIRT7; CARM1; ING2; POU2AF1; ZNF74; TCF7L1; ELF3; PLAGL2; BHLHE40; TRIM16; ZNF350; GLI2; ZNF117; PLAGL1; BATF3; STAT4; FOXG1; SLC2A4RG; WNT4; EHMT2; ZNF107; DEAF1; PITX1; FOXA1; RXRA; HOXA10; SIX1; RNF141; ZNF516; CTR9; BACH2; SMARCA1; RCOR1; MEOX2; PBXIP1; IRF4; NR2F1; ZKSCAN1; ZNF589; SMARCD3; CERS4; MNAT1; NR1H3; ELF5; TP63; TBX21; ZSCAN18; KLF10; ZNF146; LEF1; PAX5; BCL6; IRF6; EYA1; SMAD7; TRPS1; HLF; SIX2; CRYM; ZFP36L1; EYA2; YBX3; MEIS2; SOX9; HEY1; TCF4; KDM5D; SOX11; CREB1
Down-regulation 64 SAFB2; NR4A2; MTDH; PRPF6; EN1; CCNH; TULP4; BAZ2B; CEBPB; CCNC; WT1; RBM39; INSR; MED23; PHF1; ZNF512B; APEX1; C1D; ING3; RNF138; HLTF; GTF3A; BRD2; YWHAB; ZMIZ1; ELF1; KAT6B; AHR; ZFPM2; HMBOX1; ZNF91; ELK3; TFDP1; SCAND1; NR1D2; FOSL2; UBE2B; HOXC6; CSDE1; NR2F2; BRCA1; CBFB; CHD9; SFPQ; TCEB2; ENY2; SP100; MYCN; PQBP1; ZMYND8; CITED2; TSC22D1; MTF2; KLF2; ARNT2; ZBTB16; EMX2; KLF9; ZBTB38; ATF3; THAP11; ZIC1; ESR1; TBX2