Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID08160 Azd-5438 GSE70138 HA1E Human 24h 1.11uM EID0010
Types Number Response transcription factors
Up-regulation 51 SSBP2; PAX8; NCOA3; MDM4; EMX2; TCEA2; STAT2; BCL3; CBX6; TRIM16; GTF2IRD1; TFEB; ZNF212; MZF1; NAB1; ZNF264; NFAT5; TTF1; TSC22D1; ZNF226; NPAS2; RELB; PRKDC; RUVBL2; HOXA10; PCGF2; PLAGL1; ZNF529; SREBF1; NR1H3; RERE; PLAG1; ZBED2; BHLHE41; REL; SHOX2; MYRF; SOX9; SMAD1; TERF2; CUX2; PBX1; VGLL4; CTNNB1; ZNF83; BACH2; TRIP6; KDM5D; SOX11; SATB2; FOXG1
Down-regulation 84 NFKBIA; CCNA2; FOXO4; MYC; EGR1; CENPF; PTTG1; MYCL; KLF2; NR5A2; NFATC4; MXD4; JUN; CREB3L2; XBP1; KAT2B; MAF; NR4A2; BTG1; HNRNPD; PNRC1; JARID2; SOX10; HMGB3; NR3C2; SIX1; BANP; CBX3; HIC2; HMGB2; ZEB1; LMCD1; PRRX1; SUB1; ATF3; PTRF; TBX3; RCOR1; CRYM; TRIM29; SNAI2; TP63; ID4; BRD8; NR1D2; SFPQ; MYCN; PIR; TCF7L1; BIRC2; NR4A1; RUNX1; ID3; NFATC3; HOXC6; ZNF165; CARHSP1; HHEX; CREB3L1; ID1; MXI1; LIN28A; IFI16; PITX1; FOXC1; RBPMS; HOXB6; THAP11; TRIM24; RFX5; CITED2; HOXB2; HEY1; CREB1; TFAP2C; NR2F2; MAFB; EGR3; CTBP2; KLF9; ASCL1; TOB1; CEBPA; TBX2