Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID08159 Azd-5438 GSE70138 HA1E Human 24h 3.33uM EID0010
Types Number Response transcription factors
Up-regulation 224 ZNF274; ZNF264; GMEB2; PPRC1; ZNF211; ZNF232; ZNF473; MYNN; ZNF557; CEBPD; ZNF134; ZNF544; ZNF34; ZNF304; ZNF419; RNF4; ZNF432; TGS1; ZNF195; HDAC4; IRF8; ZNF606; ZNF7; ZNF551; ZNF324; SIN3B; ZNF266; ZFP36L2; ZBTB48; PAXBP1; MAFB; ZNF180; ZNF23; PAX6; ERCC3; ZNF45; BCL10; CEBPB; ZNF468; ZNF142; ZNF667; RLF; HOXD3; ZNF8; TDP2; ZNF816; HNF4G; ZNF222; SIRT7; ZNF263; FOXJ3; ZNF136; TAF5L; ZKSCAN4; RNF138; ZSCAN32; OVOL2; THAP1; ZNF235; CAMTA2; ZNF79; ZNF623; MECP2; ZNF329; ELF4; ZNF223; ZKSCAN5; SOX21; BCL6; SNAPC4; HDAC9; ZNF408; ZNF3; BRPF1; PPARD; CCNE1; MED17; ZNF410; IKZF5; L3MBTL1; CXXC1; ZNF273; DPF2; ATOH1; ZNF711; ZNF14; ZNF394; CERS6; ZNF227; ZNF562; ESR1; HOXD1; NUP62; ZNF787; ZNF239; ZBTB3; LDB1; ZNF83; COPS2; SIX3; RUVBL2; HCFC2; EP300; AFF4; PA2G4; PLAGL2; NPAS2; MAFG; ZNF84; ZBED4; ZNF529; ZNF576; RRN3; ZNF443; MECOM; FOSL1; ZNF629; MAFF; HINFP; ZNF426; SAP18; ARNT2; ZNF415; DNAJC2; BRF2; HOXA1; BRD2; SOX17; ZNF423; ZNF267; TOPORS; ZNF10; HIRA; AR; TFEC; NR4A2; TOX; RNF14; ZBTB11; CBX7; VGLL1; DACH1; HIC2; NEUROD1; ZNF226; E2F6; ZNF574; CEBPG; CUX2; ZNF354A; NR2C1; TWIST1; ZNF587; SHOX2; MYB; RUNX3; ZBED2; CNBP; PPP1R13L; ELF3; ZNF117; SATB2; ZNF91; RNF6; KLF10; ZNF22; BANP; PLAGL1; SPEN; BRD4; HLF; ZNF571; WT1; MAF; ZNF331; ID1; EYA2; CBFA2T3; NR4A3; TOB1; RERE; RCOR1; EPAS1; DBP; ETV5; NANOG; INSM1; KLF11; ZNF184; TAF1D; OLIG2; ST18; TERF1; TRIB3; ETS2; CREBZF; ZNF165; LYL1; TRPS1; TCF7L2; CHD7; RXRA; SALL2; RCOR3; ZNF512B; ZNF131; NR1H3; SPDEF; OSR2; FOXG1; SMAD7; BIRC2; BHLHE41; KLF4; EHF; NR0B1; NKX2-2; IRF6; ASCL1; SOX9; EMX2; CREB1; SOX11; E2F2
Down-regulation 115 ATF6; PAX8; ECD; CENPF; CCNA2; TP53; FHL2; GTF2A2; NFIL3; TRIM29; CCNC; HDAC6; CBX3; FOXO3; PNRC1; ARID5B; MAGED1; HMGB2; FOXM1; HIVEP2; HNRNPD; ELF5; PBRM1; PTTG1; PMF1; ZBTB38; YWHAB; HOXC6; SMARCC1; STAT5B; TCF20; FLNA; SOX4; ENO1; BTG1; ERBB2; ATF1; HDAC2; BCLAF1; TBL1XR1; IRF4; CREB3L2; DDX17; RFXANK; SOX10; AES; TBX3; HOXC10; CREB3L1; BRD3; TAF10; SMARCA2; FOXN3; NKX3-1; JARID2; RAN; EDF1; NCOA1; PHIP; TBL1X; PSMC3; MAZ; SIM2; DEK; ARNTL2; TP63; NEDD8; ZMIZ1; LMCD1; ARID4B; IFI16; KLF2; NFAT5; NCOR2; TLE4; ID2; PBX3; RBPJ; TCF12; LEF1; SAP30; FOXC1; HMGB1; PIR; PURA; NR1D2; SMARCA1; STAT6; ILF2; ZEB1; WWTR1; NFE2; SFPQ; BMI1; KLF6; STAT1; SP100; RUNX1; ZHX2; IRF7; BBX; SIX2; MED24; MYBL1; NFATC3; NFIB; AFF1; ID4; JUNB; CALR; TXNIP; TCF4; YBX3; TRIM22; ZIC1