Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID08141 Bms-387032 GSE70138 HA1E Human 24h 3.33uM EID0010
Types Number Response transcription factors
Up-regulation 385 HES1; EGR1; ZNF264; FOS; ZNF224; ZNF551; CD3D; NR4A2; PRDM14; ATF3; PEG3; ZNF701; JUN; ZNF154; SCAI; ZNF136; NFKB2; HOXD3; CEBPD; ZNF117; CHD2; IKZF2; ZNF44; MAK; SPI1; ZNF606; FOSB; MYC; ZNF667; ZNF695; ZNF391; ESR2; ZNF816; ASCL3; CARF; OVOL2; EGR4; AR; NFIX; GBX1; ZNF440; HIPK2; TP73; RFX1; ALX4; LHX6; HOXC5; ZNF345; TWIST1; SRY; POU6F2; PAX1; FEZF2; SLC2A4RG; RBPJL; MAML3; SOX5; EMX1; ZNF75D; SOX17; ZNF331; NKX3-2; FOXJ1; NR4A3; ZXDC; NOCT; SCRT1; THRB; PAX7; TBX6; HOXB8; TBX5; NR4A1; SSX7; NHLH2; ZNF682; HOXD1; ZNF423; THRA; SOX18; NEUROG2; HOXB1; NR5A1; NKX6-1; CREG1; ZNF208; ZKSCAN8; HOXB5; PRDM9; NEUROD2; ZKSCAN4; ZNF221; ZNF273; IRF1; TEF; ZNF549; SOX21; LHX3; HAND1; PRDM16; RORB; PROP1; RFX3; ZNF492; ZNF223; ZNF611; HIF3A; VENTX; ZNF550; SIX6; L3MBTL1; PRDM5; MYCBP; TFDP3; NEUROD6; HNF4G; DOT1L; HES2; ZNF544; FOXD3; ZNF749; EHMT2; ATOH1; FOXE3; ZNF688; POU5F1B; HDAC9; ZIM2; SSX3; EPAS1; ACTL6B; SOX1; HEYL; ZNF235; MLLT1; HESX1; TULP1; ZSCAN2; DLX6; ZNF362; NACA2; ESRRB; ZNF771; ZNF471; ZNF135; PDX1; VGLL1; ZNF467; GBX2; ETV3; ZFHX2; ATF7; TCEA2; REL; ZNF10; MAPK8IP1; ATF6B; THAP10; ZNF665; ZNF304; NR0B2; ZNF257; HDAC11; TFDP2; CERS6; BCL11A; IRF6; MZF1; BRDT; RSF1; ZFP2; MEOX2; POU2F3; NFAT5; PLAGL1; OVOL1; HAND2; RARG; MECP2; ETV2; SIX3; POU4F3; HDAC5; DLX5; SMAD6; HSF1; WT1; ZNF43; TCF21; RORC; CIR1; GTF2A1; FOXA1; BARX1; MNDA; AIRE; HOXC8; PRDM12; ZBTB7C; ZNF358; RBL2; ZNF536; ZNF493; ZNF573; MEIS2; SKIL; MED25; DMRT1; SSBP3; SPDEF; ZNF407; NFKBIB; GSC2; ERBB4; MDM4; NR2E1; TCEA1; CIITA; ZNF711; HIVEP3; NR1H4; ZNF254; POU1F1; SIX5; EVX1; STAT2; NPAS1; ZNF91; TLX1; ZNF214; EBF2; ZBTB48; HOXD13; LIN28A; DBP; TLX3; ZNF195; DCC; NR5A2; LDB1; SMARCB1; PHOX2A; ZNF623; ZFPM2; ZNF671; CALR; EMX2; CREM; ING4; KLF15; MDM2; SHOX2; SOHLH2; TGFB1; PITX1; PEX2; KAT2B; TDP2; MAP3K10; ZNF211; ZNF132; MAFK; LZTR1; ZNF529; ZNF415; MECOM; JUNB; ESR1; POU3F2; ATN1; EGR2; ARNT2; WNT4; ZSCAN31; FOXF1; CALCOCO1; SRCAP; ZNF205; IRF3; ZIC3; HOXC4; TBX21; CEBPE; SMAD5; ZNF222; MYRF; GFI1; ZBED2; MSX1; SIM2; SAP18; EP300; PBX1; MYCL; PRDM1; SKI; HLX; MYCN; HOXB13; DLX2; ZNF528; ISL1; SALL2; ZSCAN18; RING1; ZNF329; GRHL2; CREBL2; BCL11B; SOX3; JUP; ZNF107; TOX; ZBTB20; NR0B1; ZNF253; CBX7; BHLHE40; CBFA2T3; AEBP1; MYT1L; GATA1; PBXIP1; EYA1; NFIC; PRRX1; TCF7; PHOX2B; HIC2; ZFHX4; NKX2-2; CUX2; TXNIP; INSM1; ZNF350; HMBOX1; EGR3; ZNF184; HEY1; NANOG; ZNF160; FOXL2; HOXD10; TERF1; OSR2; GATA2; AES; FOXF2; CRYM; HOXD11; HMGN3; PAX6; MXI1; HLTF; FOXG1; FOXA2; MKL2; STAT4; EHF; HOXB6; ARID1A; HOXB2; TRIB3; MEIS1; ETV5; ZNF652; NR1H3; LITAF; LEF1; ZNF721; ZFP36L1; RBFOX2; STAT1; ID3; KLF2; IKZF1; NR2F1; MEF2C; TRIM22; SOX2; ELF3; SOX11; SNAI2; ID1; E2F2
Down-regulation 178 TLE1; CCNA2; CRK; SUV39H1; NUP62; XBP1; FHL2; MYBL2; FOXO3; PUF60; HNRNPD; NFKBIA; ECD; CENPF; UBE2I; SCAND1; USP22; RBM14; TBP; NFIL3; PAX8; EED; AATF; ZNF672; TP53; ZNF146; BASP1; TAF9; HDAC2; TRIM32; VEZF1; EZH2; BRD3; SNW1; SMARCA5; NPAT; HOXA10; BLM; SMAD3; TAF5; SUZ12; SOX4; ZMIZ1; ING2; MED1; DEK; DNAJC2; MBD2; PATZ1; ARID4B; NCOA6; ADNP; HOXA5; ZBTB24; CARM1; BRPF1; FOXK2; WHSC1; PREB; HMGB2; NRF1; MED6; KAT7; SMAD4; BAZ1B; TRIM27; CDK7; BRCA1; MED13; GTF2IRD1; RBPJ; ELF5; PTTG1; PHF20; DPF2; CCDC59; RNF111; ZNF263; REPIN1; PCGF2; CNOT1; ASXL1; MAX; CRY1; SETD2; APEX1; BCLAF1; CTCF; SFPQ; CHD1; MED20; DDX5; SOX10; STAT5B; ZNF189; RBBP4; ATF1; CEBPG; SAP30; JARID2; BAZ1A; HIVEP2; SMAD2; KAT8; HMG20A; NFKB1; GATAD2A; HMGB1; CENPB; TRIM29; TBL1XR1; ZNF410; TRIM16; CBX3; NR2F6; BRIP1; TBL1X; RBM39; YAF2; CEBPZ; CEBPB; BMI1; NELFB; FOXO1; RNF138; FOSL2; RARA; YWHAB; CCNC; SSRP1; ZBED1; TCF12; TBPL1; COPS5; MYBL1; MNAT1; BRD8; SMARCD3; NCOA1; ZNF302; NFIB; ZMYM2; RBBP7; TGFB1I1; PPARGC1A; ZNF281; ELF1; HOXB7; NRBF2; NKX3-1; TSC22D2; NFYB; NCOR2; ELK3; RXRA; SMAD1; PURA; ZEB2; SOX9; ZBTB16; ZFP36L2; FOXC1; CTBP2; RBPMS; KDM5D; KLF6; KLF4; BTG1; ZBTB18; SATB2; ABL1; PBX3; MAFB; NR2F2; HOXC6; THAP11; RELB; NR3C1