Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID08140 Bms-387032 GSE70138 HA1E Human 24h 10uM EID0010
Types Number Response transcription factors
Up-regulation 445 EGR1; ZNF264; TWIST1; ZNF701; ZNF695; ZNF75D; PRDM14; SOX21; ZNF606; ZNF391; ZNF136; ZNF224; SPI1; FEZF2; CHD2; ZNF492; MAK; ZNF223; ZNF440; ZNF154; NHLH2; MAML3; THRA; ZNF682; ZNF816; HOXD3; ZNF257; SCRT1; FOXD3; DOT1L; LHX3; POU6F2; ZNF423; TP73; PEG3; L3MBTL1; ZNF551; ZNF235; NEUROG2; NEUROD4; ZNF362; ZKSCAN8; TCEA1; TFAP2A; ZFPM2; SCAI; POU2F3; SRY; ZNF345; HNF4G; TLX3; ZNF208; SOX5; ZNF749; SSX7; GBX1; ZKSCAN4; ZNF544; HOXB8; EMX1; RFX1; ASCL3; RFX3; ALX4; REL; CARF; RORB; ZNF688; NEUROD1; ZNF141; NEUROD2; ZNF467; FOXO4; ZNF778; NKX3-2; PRDM5; ZNF471; OVOL2; FOXE3; NR4A2; ZNF669; ZNF180; ZNF273; MYCBP; NR5A2; HESX1; PAX7; IKZF3; CEBPD; PRDM9; TAF4B; ZNF343; TBR1; ZNF407; MECOM; ZNF573; ZNF117; THAP10; RBPJL; MEIS2; VENTX; SOX18; ZNF674; ZNF157; HEYL; ZNF549; ATOH1; ZNF80; HOXB5; ZNF667; TCEA2; MNX1; ZNF274; NEUROD6; NFKB2; MXD4; ZNF195; LHX6; MECP2; THRB; BRDT; SOX1; HOXA2; DLX5; SP4; TBX5; ATF7; WNT4; SMAD6; ZNF557; HOXD1; ZNF214; ZNF550; GSC2; SIX3; SOX17; ASCL2; UTF1; ZNF611; ACTL6B; ZNF81; IKZF2; HIPK2; BARX1; ZBTB44; POU3F3; GCM2; SUPT7L; PDX1; FOXB1; CREG1; IRF6; DMRT1; VGLL1; TFDP2; NACA2; FOXD2; ZNF442; ONECUT1; ZNF44; ZNF780B; MYRF; ZNF174; HAND1; ESR2; HOXB1; MEOX2; ZNF493; TFDP3; POU1F1; ZNF225; VHL; ZNF835; ZNF221; ZNF814; ZNF331; PAX4; PEX2; ZNF132; ZNF135; ZIM2; AR; FOXL1; MED31; OVOL1; TULP1; HES2; ZNF415; CBX8; POU4F3; PRDM16; SKIL; ASH1L; STAT2; ESRRG; CDX1; ZBTB7C; VPS72; ING4; TEF; ST18; HOXC5; GBX2; ZNF652; PHOX2A; ZNF304; HDAC5; ATF6B; DCC; HDAC9; ZNF665; SOX30; ZNF112; FOS; ZNF334; ZNF771; CUX2; CBX2; ZBTB3; GRIP1; ZIC3; MAPK8IP1; ETV3; ZFP2; CD3D; RORC; ZNF484; EHMT2; ZNF10; ZBED2; FOXJ1; MLLT1; LBX1; CIITA; E2F1; BNC1; PAX1; TRIB3; HIF3A; ISL1; KLF8; ZFY; ZNF41; ZNF711; HAND2; ZNF211; ARID3A; PAX6; CBX7; MED25; HMBOX1; NFAT5; MSX2; FOXF1; ATF3; NR2F1; ETV2; PIR; ZNF623; ZNF226; AIRE; HOXD12; POU4F2; HBP1; MDM2; CALR; ESRRB; SOX3; CBX4; NR5A1; LZTR1; NR0B2; NR2E1; NR1H4; CREM; ZFHX4; TCF21; ZNF586; PROP1; NFATC4; SSBP3; RARG; BCL11A; ONECUT2; MYCL; ZNF254; ZNF710; FOXA2; ZNF93; PITX1; PBX1; TAF6L; RSF1; INSM1; EPAS1; LITAF; SPDEF; THAP9; HOXC8; PAX3; RFX2; MZF1; ZNF350; ARNT2; ATN1; ZNF671; CDX4; CREBL2; RORA; ZNF287; DBP; NFIX; HOXD13; SIX6; GCFC2; NKX2-5; ZNF536; FHL5; PRDM10; MDM4; AFF2; SALL2; MAF; ESR1; NKX2-2; ZKSCAN7; ZBTB20; ZNF675; STAT4; KAT2B; EGR2; ZNF562; TAF7L; CDIP1; TSC22D1; TDP2; KLF15; NR1I3; HIC1; GRHL2; ZBTB7B; LIN28A; EBF2; HHEX; ZNF107; LDB1; ZNF329; ZNF253; ERBB4; PHOX2B; RNF141; NR1I2; WT1; FOXF2; CAMTA2; TBX19; CBFA2T3; SKI; IRF8; SLC2A4RG; PRDM1; EMX2; SMARCB1; JUP; ZNF3; EGR4; ZNF528; PKNOX2; RING1; KLF13; NR4A1; SRCAP; SSX1; ZNF532; MNDA; SUPT3H; PGR; GATA1; TOX; TCEB2; CNOT3; HLX; CALCOCO1; ZSCAN31; TGFB1; TCF7; AES; ZNF184; ID3; SHOX2; HIC2; BHLHE41; ZNF200; OLIG2; NR4A3; TRPS1; NFIC; TBX21; LYL1; MYCN; EN2; TULP3; FOXL2; MSX1; INSR; ELF3; GFI1; EYA1; ZNF160; PRRX1; HEY2; SOX2; GFI1B; ZNF721; E2F5; ZNF91; HLF; HOXD11; NANOG; NFE2L3; AEBP1; TCF4; NR0B1; SOX11; NR1H3; HMGN3; FOXG1; MED24; RBFOX2; OSR2; MEIS1; HOXB6; TRIM22; SIX2; ZEB1; EYA2; MEF2C; ID1; TXNIP; HEY1; GATA6; LEF1; IKZF1; E2F2; GATA2
Down-regulation 202 CCNA2; CRK; FHL2; NFKBIA; EED; MYC; XBP1; NUP62; PUF60; ECD; NFIL3; HNRNPD; TLE1; FOXO3; SUV39H1; HOXA10; USP22; TBP; BHLHE40; MAX; CENPF; RBM14; NKX3-1; HDAC2; TRIM32; SNW1; SCAND1; TP53; MED1; CDK2; UBE2I; PRPF6; FOSL1; NPAT; MYBL2; ARID5B; DNAJC2; CDK7; VEZF1; NCOA6; BCLAF1; AATF; PAX8; RFC1; CCDC59; EZH2; FOXJ3; NRIP1; BRD3; SOX4; BAZ1B; TAF9; ADNP; ZBTB1; KAT7; MED13; GATAD2A; ZBTB24; HMGB2; ZNF146; HIF1A; PPRC1; MED6; ZMIZ1; TCF20; DEK; ATF4; REST; RNF111; DDX54; BRCA1; CRY1; SMARCA5; SUZ12; PCGF2; TRIM27; KLF6; YWHAB; MBD2; CTR9; HIVEP2; TAF5; ING2; BLM; CITED2; ATF1; CEBPG; KAT8; ZNF263; BATF; RBPJ; SMARCE1; KLF10; HOXC10; CNOT1; SETD2; BAZ1A; AFF1; KDM2A; SERTAD2; NFKB1; ELF5; WHSC1; SFPQ; CARM1; CTCF; ZBTB11; CHD8; ASXL1; CEBPZ; NCOA4; PATZ1; REPIN1; JARID2; BMI1; CCNC; BASP1; ADNP2; MGA; PBX3; CEBPB; ORC2; FOXC1; ZNF672; SIX1; BRIP1; HMG20A; RREB1; KLF4; CBX3; ZNF410; RRN3; PURA; APEX1; NPM1; TRIM16; TBL1XR1; DNMT3B; UBE3A; RNF138; TRIM29; NELFB; SAP30; ZBED4; POLR2A; FOXD1; RUNX1; BCOR; ELK3; HOXC6; BTG1; PHF20; ZNF574; BATF3; HDAC7; PSMC3IP; TBL1X; TCF12; ZMYM2; SMARCA2; SF1; SMARCD3; ZNF281; EDF1; HOXA5; XRCC6; ZNF217; RELA; RBM39; ZNF302; JUND; HMGB1; MAFF; ERBB2; SMAD1; SMAD4; BRD8; FLNA; IKBKAP; IRF7; SIAH2; NCOR2; ING3; RXRA; MYBL1; RBBP4; DMTF1; HOXA11; MNAT1; TSC22D2; STAT6; SMAD7; SPEN; VGLL4; ZBTB18; SOX9; ZIC1; SATB2; MAFB; KDM5D; NR3C1; ABL1