Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID08134 Canertinib GSE70138 HA1E Human 24h 10uM EID0010
Types Number Response transcription factors
Up-regulation 221 NFKBIB; CEBPD; FOXO4; PEG3; ZNF117; ZNF544; TRIB3; CEBPB; ZNF224; TP53; ZNF195; MNT; ZNF141; ZNF222; ZNF665; MXI1; ZKSCAN4; ZNF155; ZNF273; PIR; DDIT3; CHD2; HOXD1; ZNF573; ZNF44; ZNF75D; RSF1; ZNF701; ATF5; ZNF225; MED12; INSR; ZFP69B; ING4; ZNF43; PRDM10; ZNF91; ZNF136; ZNF557; ZNF223; CARF; NR1H4; ZNF688; ZNF695; HDAC5; TFAP2A; CALCOCO1; ZNF23; MZF1; BPTF; ZNF440; ZNF682; TDP2; ZNF257; ZNF778; SPI1; LPIN2; CREG1; SIX6; ZNF345; ZNF232; CIR1; NEUROD1; MDM2; FEZF2; ZNF219; ZNF432; ZNF227; CDIP1; NFAT5; HBP1; IRF3; ZNF606; NR5A1; HTATIP2; ZNF675; NFATC4; ZNF264; ZNF331; STAT2; THAP10; ZNF177; ATF4; SUPT4H1; NR1I2; PIAS4; TBX1; SOX18; SOX5; ZNF226; ZNF304; SOX12; ZNF254; ZNF85; SCAI; PNRC1; ZNF415; ZNF45; JAK2; ZBTB3; ATF3; PFDN5; PRDM2; ETV5; KLF11; ZBTB43; CBX7; CEBPG; TRAK1; ZBTB44; GTF2F1; TAF11; ST18; IRF1; L3MBTL1; ARNT2; DMRT1; ZNF24; NHLH2; ZNF426; ZNF419; NR0B1; TP63; ZNF10; NR2C1; CD3D; ZNF430; RORA; SETDB1; ZNF350; LDB1; CREM; SOX13; NR4A2; HINFP; ZNF32; NFIX; PCGF1; TRIM22; PHIP; ZNF84; SOX3; SALL2; ID2; ZNF83; ZNF529; NPAS2; PHF1; SP2; MNDA; HLX; ATN1; MAFF; PBXIP1; ZNF107; TSC22D3; MXD1; ZNF611; SALL1; UBE2B; HMGA1; ZSCAN18; VGLL1; SMAD6; CERS4; ZNF354A; CBFA2T3; KAT2B; RBPJ; CNOT2; BRD4; ZNF580; COPS5; FOXF2; SAP18; VPS72; TULP3; MAFG; TAL1; NCOA2; EMX2; TSC22D1; BCL11A; GTF3A; PAX6; IFI16; ZNF160; CITED2; HDAC9; HOXC10; NR1H3; BCL3; BCL6; ZMYND8; KAT6B; NR4A1; TGIF1; BHLHE41; TRIM29; RFX5; YBX3; NKX2-1; BTG1; NCOA3; HOXB2; ZNF423; TCF21; ZNF721; FOXG1; SPDEF; AEBP1; SOX11; INSM1; TBX3; ETV1; OSR2; ID1; MAFB; MEF2C; SNAI2; NFATC3
Down-regulation 101 CCNA2; LOXL2; MYCBP; MYBL2; MYC; TLE1; CENPF; BCLAF1; HNRNPD; TGFB1I1; SOX4; FOXO3; KLF7; EZH2; HDAC6; KMT5A; RUVBL1; ZBTB18; FLNA; FHL2; EED; PTRF; HOXA10; JUN; NRIP1; DNAJC2; PITX2; ARID5B; MAGED1; HES1; WHSC1; SUB1; UBP1; HMGB2; RHOA; SFPQ; VEZF1; RNF4; ELK3; SMAD2; IRF4; HDAC2; TBL1XR1; MLXIP; RB1; GATA6; BLM; SMAD7; TCF3; TRRAP; SND1; NPAT; MBD2; SETD3; RARA; SLC2A4RG; RBBP7; ZBTB1; KLF6; TFEB; CREB3L1; TFDP1; RBM14; EDF1; PTTG1; BHLHE40; SP3; DMTF1; PURA; ZFHX4; ING3; SMAD4; SF1; SMARCC1; CENPB; NEDD8; NCOR2; BASP1; YWHAB; NR2F2; MYBL1; ETS1; BMI1; CUX1; HOXB7; ARNTL2; ZNF281; KLF2; TLE4; RBBP4; CEBPZ; HLTF; PLAGL1; RBPMS; ZBTB38; KLF9; HOXB6; TBL1X; CTNNB1; NR3C1; SATB1