Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID08133 Afatinib GSE70138 HA1E Human 24h 0.04uM EID0010
Types Number Response transcription factors
Up-regulation 31 SSBP2; KDM5A; NCOA3; NR4A3; ZNF432; ZNF165; BRIP1; HLX; HOXC10; KLF9; NAB1; BCL11B; NFAT5; NR4A2; ZNF468; SSX1; EGR2; ZNF281; AHR; SFPQ; ZBTB38; ATF7IP; MEIS1; NR1D2; TBX2; ATF3; NKX2-2; BHLHE41; WT1; SNAI2; ID3
Down-regulation 20 UBE2I; ZNF430; ZFP36L2; CTBP2; PRRX1; POU4F1; IRF6; ZNF264; SIAH2; MBD2; ZNF91; LYL1; SOX17; ETV5; HOXB6; ASCL1; NR2F1; BTG1; CREB1; THAP11