Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID08132 Afatinib GSE70138 HA1E Human 24h 0.12uM EID0010
Types Number Response transcription factors
Up-regulation 15 YEATS4; MDM2; PCGF3; NEUROD1; WWC1; CNOT2; TAF9B; PAX6; DNMT3B; SMAD1; ELF3; MECOM; DACH1; ZIC1; CREB1
Down-regulation 28 EGR1; CENPF; ZFP36L2; RBBP7; EGR3; TGIF1; MAGED1; PRRX1; FOS; IRF4; HMGB2; MXI1; POU2AF1; HOXB2; ZSCAN18; CALR; MYCN; SMAD7; BHLHE41; ZBTB16; YBX3; HOXC6; MYRF; KDM5D; THAP11; ID1; ID3; TBX2