Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID08131 Afatinib GSE70138 HA1E Human 24h 0.37uM EID0010
Types Number Response transcription factors
Up-regulation 22 SOX2; POU5F1B; FOS; NANOG; NFKB1; LIN28A; TRIM22; DNMT3B; ZNF532; KLF11; TERF1; BTG1; YBX3; TGIF1; ZBTB16; FOXG1; BACH2; INSM1; PBX3; TOX3; OSR2; HOXC6
Down-regulation 18 EGR1; HDAC1; NEDD8; ERCC3; ZSCAN31; ZNF12; RBBP4; ID4; GATA6; SOX9; BHLHE41; CHD7; CREB1; HMGN3; THAP11; LEF1; TXNIP; GATA2