Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID08128	Afatinib	GSE70138	HA1E	Human	24h	10uM	EID0010

Response Information :

Types	Number	Response transcription factors
Up-regulation	114	TSC22D3; TRIB3; CEBPB; DDIT3; PAX8; ATF4; ZNF23; ATF5; FOXO4; ZBTB7A; ZNF8; TRIP4; ZNF688; ZKSCAN4; HOXD1; ZNF195; HTATIP2; RYBP; EGR1; BPTF; HIVEP3; ZSCAN9; MDM2; BANP; STAT2; PCGF1; CIR1; FOSL1; TDP2; CAMTA2; ZNF430; ESRRA; ZNF443; HLX; PPARD; ZNF43; ZNF91; CREM; CEBPG; ZSCAN16; ZNF45; UBE2B; ZNF500; ZBTB43; PIR; ZNF331; AGO2; CTCF; LDB1; NR4A2; NCOA6; RNF6; SREBF1; ZNF44; ZNF184; ZNF544; ZNF304; NFAT5; MED13; ZNF24; PLAGL2; CBX6; NFE2L1; MXI1; TOB1; BRD2; ATF3; MED1; NCOA1; HDAC9; PHF1; RBBP5; SALL2; HMGA1; LPIN2; SSX1; PHF20; KAT8; ARNT2; SHOX2; TSC22D1; AFF1; TGIF1; RREB1; JARID2; FOS; MAFB; TWIST1; BTG1; NRBF2; KLF11; TERF2; CBFA2T3; TCF7; ID1; PEG3; ZNF160; FOXO1; HOXC10; RXRA; MNDA; RFX5; NCOA3; IRF7; LEF1; EMX2; GTF3A; ESR1; TRIP6; ZIC1; TXNIP; THAP11; CREB1; NFATC3
Down-regulation	84	LOXL2; MYCBP; CCNA2; MYBL2; FHL2; DNMT1; ARID5B; MYC; CDK2; PARP1; NFKBIA; SMAD3; HOXA10; HES1; PTRF; TGFB1I1; RBPMS; NRIP1; KMT5A; NELFB; SOX4; TFDP1; FLNA; CENPF; ID4; BCLAF1; HNRNPD; FOXM1; HDAC1; ZBED2; GLI2; WWTR1; SLC2A4RG; EDF1; SFPQ; MLXIP; GATA6; RBBP7; MBD2; RBBP4; DLX2; CHD3; MYBL1; ASH2L; KLF7; WWC1; GTF2I; WNT4; ERBB2; TLE4; GFI1; SOX15; PITX2; POU2AF1; SMAD7; SMARCA2; SUB1; FUBP1; PLAGL1; HMGB2; ARNTL2; CALR; HOXA5; TBL1XR1; MED21; FOXF1; HHEX; SIAH2; NKX2-2; NANOG; NFIB; ELK3; HOXB6; FOSB; TCF21; PBX1; PBX3; NR2F1; KLF6; KLF10; MEIS1; PSIP1; MEIS2; INSM1