Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID08126 Celastrol GSE70138 HA1E Human 24h 0.12uM EID0010
Types Number Response transcription factors
Up-regulation 39 NFKB2; ZNF544; HDAC9; NFAT5; ADRB2; SMARCD3; ZNF189; ZBTB18; HOXD1; ZNF217; ZNF175; ZFP36L2; PEG3; ZEB2; RBBP4; SIAH2; FOS; NPM1; SMARCA2; TRIM29; MAGED1; TXNIP; ZNF331; NR1D2; BBX; TFAP2C; RUNX1; RBBP8; MYB; NFE2; IRF7; TGIF1; SMARCA1; EGR3; WT1; KLF9; SNAI2; TRIM22; ESR1
Down-regulation 40 NFKBIA; MED21; MTA1; KAT2B; WNT4; IRF8; NRIP1; EN1; HOXC10; MSX1; DLX5; BATF3; RBFOX2; POU2AF1; EYA1; MECOM; NFATC3; BLM; HMGN3; FOXA2; ID1; HEY2; MED24; PITX1; ID3; TGFB1; LEF1; TCF4; HEY1; PAX5; INSM1; MAFB; NR2F2; FOXF1; MEIS1; THAP11; SATB1; RELB; TBX2; GATA2