Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID08125 Celastrol GSE70138 HA1E Human 24h 0.37uM EID0010
Types Number Response transcription factors
Up-regulation 40 STAT5B; CEBPB; TRIB3; TBX3; HMGA2; JAK2; TCF15; HIC2; UBE2B; BAZ2B; TSC22D1; SOX9; DDIT3; HMGA1; PEG3; ZNF467; RNF141; ZNF302; NRBF2; ZFPM2; NFE2; PBXIP1; TAL1; HTATIP2; TRIP6; TCF7; KLF2; ST18; CITED2; ZFP36L1; KLF4; DACH1; ARNT2; BTG1; ATF3; AHR; HEY1; SNAI2; THAP11; EMX2
Down-regulation 29 NFKBIA; MYBL2; SLC2A4RG; IRF4; IRX5; HDAC9; XBP1; SOX4; ZBTB1; KLF10; MLXIP; BHLHE40; GFI1; CRYM; WWTR1; GRHL2; SFPQ; IL16; SMAD7; SUB1; MAGED1; NKX2-1; HMGN3; WT1; ID4; RELB; ESR1; SATB1; TBX2