Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID08124 Celastrol GSE70138 HA1E Human 24h 1.11uM EID0010
Types Number Response transcription factors
Up-regulation 269 HES1; FOS; ZNF274; MED17; GABPB1; ATF3; ARID4B; CEBPD; FOXO4; NR4A2; TLE1; NR4A3; ID2; ZNF34; AFF4; CEBPB; DDIT3; GATA3; MYC; KLF11; TAF4B; KLF4; NKRF; KDM5B; ZKSCAN5; ZNF264; ZNF10; ZNF304; ZNF235; RLF; NR4A1; EGR1; ZNF227; ZNF84; HIC2; ZNF222; RSF1; RYBP; MAK; FOSB; ZNF184; ZNF211; GABPA; PPARG; CREM; ARID5B; ZNF140; DLX2; ZBTB11; ZNF8; ZNF419; ZNF134; ZNF180; JAK2; HOXA1; YEATS4; BRWD1; MAML1; ZNF267; BCL6; ZNF45; TRIB3; ING1; TGS1; OSR2; ZNF217; ARID4A; YEATS2; HIPK1; TAF5; HBP1; TDP2; ZNF432; ZNF141; ZNF468; ZNF225; ZNF551; ZNF189; MDM2; ZNF473; PNRC1; BCOR; CIR1; TAF9; PRDM10; LHX6; MXD1; TRIM33; ZFP69B; TTF1; ZNF606; BRD2; MEF2D; ZBTB39; ZNF273; BCL10; TGIF1; ZNF557; PRDM2; NEUROD6; DR1; PRDM4; HINFP; TAF1A; SOHLH2; NHLH2; SKIL; ZNF614; CHD1; ZNF623; EBF2; FEZF2; FHL5; GCFC2; PHIP; HIRA; ZNF136; RNF138; SOX18; MAFB; REL; CDK7; NCOA2; MNDA; SUPT4H1; ZBTB43; ZNF394; ZBED2; FOXA1; RRN3; HESX1; ZNF711; IRF8; ELF4; TFAP2C; ZNF329; RUNX3; AGO2; ZNF195; ZZZ3; NR2C1; ZNF331; ZNF345; SOX4; ZNF131; TSC22D3; ZNF354A; PSPC1; HIVEP1; ATF4; CRY1; CBFA2T3; ELF3; ARNT2; HSF2; ID3; TBPL1; MTF2; DACH1; ZNF175; HOXB7; PLAG1; TSC22D1; UBE2B; YAP1; HLX; HEY1; ERF; HAND1; ID1; RCOR1; CUX2; ETS2; EN2; THAP10; NAB2; ZNF200; EP300; PBX1; AHR; IRF4; SHOX2; TWIST1; JARID2; HOXA10; ZHX2; PITX2; CITED2; EN1; KLF5; MEOX2; SMAD6; ZFP36L2; ZNF232; HOXA11; TCF7L2; EMX2; TDRD3; FOSL2; ZNF268; SOX13; ZNF544; TERF1; TLE4; CBX7; MEIS2; ZNF117; SSX1; TAL1; ZNF532; TBX3; BACH2; ZFPM2; CHD9; CNOT2; BATF; CAMTA1; GATA2; ZNF529; RBPJ; ZNF611; SNAI2; MITF; NFYB; BAZ1A; SAP18; CD3D; JUNB; EGR3; LIN28A; SMAD7; AEBP1; RNF6; GATA6; WWP1; BMI1; SOX17; DLX5; NR0B1; SATB2; NFE2L3; HHEX; ZNF652; ATF7IP; IRF6; SPIB; ZNF423; RBPMS; ZFP36L1; TOB1; CRYM; ERG; FOXO1; ISL1; KLF10; MECOM; HTATIP2; SOX11; KDM5D; LEF1; ESR1; FOXG1; MSX1; FOXF2; HOXC6; SPDEF; MEF2C; ADRB2; THAP11
Down-regulation 71 HDAC6; PUF60; ATF6; SUV39H1; TP53; TAF10; PRKDC; ZHX3; XBP1; CBX5; RBBP7; SND1; MMS19; CALR; MXD4; PFDN5; MAGED1; SREBF2; LIMD1; TGFB1I1; ENO1; RBBP4; NEDD8; WWC1; REPIN1; WHSC1; CENPB; SCAND1; SMARCB1; MTA1; USF2; DEAF1; WWTR1; SMAD3; SFPQ; DDX17; EDF1; AES; PTRF; MLXIP; ASCL1; RHOA; SMARCD3; TFEB; TADA3; STAT6; SUB1; MED24; FLNA; ERBB2; MYBL1; PSMC3; TGFB1; TRIM22; RUNX1; LITAF; NFIB; NFIC; NCOR2; PITX1; PBX3; TBL1X; CTNNB1; NRIP1; FOXC1; GTF3A; BHLHE41; ZBTB38; SMAD1; TOX; RELB