Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID08123 Celastrol GSE70138 HA1E Human 24h 3.33uM EID0010
Types Number Response transcription factors
Up-regulation 83 PSMD9; FOXO4; PRDM14; ZNF423; PCGF1; HIC2; SOX17; ID2; CEBPG; DLX5; TFAP2A; CEBPB; OVOL2; ZNF232; TCEA1; SMARCB1; NKX3-2; KLF4; TWIST1; THAP10; NFKBIB; SAFB; HAND1; CDX2; SOX13; ARNT2; ZIC3; CEBPZ; ZNF415; ID3; FOXJ1; ID1; NR4A2; ATF3; BCL11A; TGIF1; LIN28A; SNAI2; DNAJC2; HMGA2; HOXA1; SIX3; CBX7; POU2AF1; VPS72; MNDA; EN1; TDP2; PIR; ZNF165; PHOX2B; HMGB3; HMGA1; FOS; ZNF331; HIRA; HDAC9; CRYM; ISL1; EMX2; ENY2; SPDEF; ZBED2; DDIT3; HEY1; NANOG; HOXD1; TRIB3; TFAP2C; CBFA2T3; MYB; PAX6; IRF6; FOXG1; HOXB2; KLF5; FOXF2; MEIS2; HMGN3; ESR1; WT1; SOX11; MEF2C
Down-regulation 79 CRK; FOXO3; ZKSCAN1; KDM5A; ARID5B; TAF7; ZNF430; MGA; SMARCD3; VEZF1; CENPF; WWTR1; NRIP1; TRIM16; BACH1; MXD4; PRKDC; PTRF; KDM5B; NCOR1; ENO1; KMT2A; LPIN2; ZMIZ1; ZNF189; MED13; REPIN1; ZNF281; REST; CTR9; ZNF292; BRIP1; NFIB; SIX1; GLI2; XBP1; NCOA1; ZNF148; TCF12; BAZ2B; LMCD1; FLNA; ZBTB18; ZEB1; NKX3-1; SIAH2; BHLHE40; FOSL2; NR2F2; ATF7IP; CHD9; AFF1; EGR2; MAGED1; ZMYM2; MXI1; RREB1; SMARCA2; TRIM24; HLTF; NFATC3; CREB3L2; NCOR2; ZBTB38; CUX1; NR1D2; TBL1X; TSC22D2; MYBL1; KLF6; ASCL1; TRPS1; NFE2; LITAF; SMAD1; EGR3; TOX3; KDM5D; NR3C1