Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID08122 Cgp-60474 GSE70138 HA1E Human 24h 0.04uM EID0010
Types Number Response transcription factors
Up-regulation 510 ZNF264; EGR1; FOSB; PRDM14; FOS; ZNF224; ZNF551; SOX5; SRY; ZNF544; ZNF701; ZNF440; ZNF695; NR5A2; MYC; FEZF2; FOXD3; ZNF391; CARF; CHD2; SCAI; MAML3; ZNF154; POU6F2; SOX17; DOT1L; SOX21; HOXA3; REL; OVOL1; ATOH1; THRB; SPI1; IRF6; BCL11A; ZNF345; ATF3; ZNF75D; CEBPD; ZNF235; RFX1; NFKB2; ONECUT2; ZNF208; RFX3; EGR4; LHX3; ZNF682; NR4A2; HEYL; HNF4G; ZNF362; ZNF358; TP73; NHLH2; ZIC3; SOX18; ASCL3; HAND1; NR6A1; TULP1; HNF1A; HOXB1; SCRT1; CDX1; NEUROG2; RBPJL; VENTX; FOXO4; OVOL2; TWIST1; EMX1; ZNF257; ZNF557; ONECUT1; GBX1; SKIL; TEF; PARP1; ALX4; KAT2B; ZNF749; ZNF669; ZNF471; HDAC5; HIPK2; AR; ASH1L; TBX5; BRDT; ZNF550; POU3F3; TFDP2; ZNF117; NFIX; ZNF467; NEUROD2; ZNF225; NR5A1; FOXB1; VGLL1; GBX2; NKX2-8; ZNF221; PRDM9; CRX; LIN28A; TONSL; MAK; ZNF136; ZXDC; POU2F3; ZFY; SSX7; UTF1; ZNF273; CIITA; ZKSCAN8; VHL; NPAS1; EVX1; EPAS1; FOXL1; HIF3A; ZNF33B; NEUROG1; ZBTB7C; GSC2; MLLT1; ZNF254; ZNF549; RFX2; ZNF771; LHX6; SSBP3; ZNF814; ZNF667; ZNF155; NEUROG3; ZNF223; CD3D; FOXH1; FOXE3; ZNF492; SIX6; FOXA1; ZSCAN2; MYCBP; SIX3; ZFHX2; ZNF80; DLX6; RORA; TBX6; HLX; L3MBTL1; EHMT2; ETV3; FOXJ1; WNT4; BARX1; HOXB5; TLX1; AIRE; HES2; HOXB8; TBR1; ZNF652; ZNF573; ZNF8; ZNF407; ETV2; POU4F3; POU1F1; NKX6-1; NEUROD4; IRF1; TBX10; HNF4A; ZNF674; CREG1; LBX1; ZNF81; ZNF195; FOXA2; ZNF343; ZNF780B; ZNF219; SIX5; MYCN; MNX1; TSC22D1; ZNF493; ZNF816; NKX3-2; TLX2; ZKSCAN4; TCEA2; NR1I2; TBX1; HDAC9; MAPK8IP1; SOHLH2; TLX3; NKX2-5; ZNF44; CUX2; ZNF710; PAX7; KMT2D; PAX6; PDX1; FOXN2; ZNF141; HDAC11; ZNF10; MXD4; ERBB4; NFATC4; ZBTB7B; PAX1; ZNF3; ZNF688; DCC; MED12; PRDM5; NR2E1; HOXD3; SKI; INSM1; SOX14; ESR2; SOX3; SP4; THRA; CBFA2T3; BHLHE40; LMX1B; ZNF835; ZNF480; NACA2; GRIP1; ASCL2; ACTL6B; ING4; ZNF611; HAND2; HOXC5; PAX3; ZNF43; SOX1; GCM2; KLF8; CDIP1; DMRT1; EP300; HOXA6; ATF7; PRDM12; HOXD1; ZIM2; ARRB1; ZNF41; PROP1; PRDM1; ETS2; HESX1; MYCL; ZNF157; MSX2; DLX5; ZNF606; TAF6L; MYT1; SUPT6H; RARG; HOXD12; ESRRB; TFAP2A; ZXDB; ATF6B; SSX3; LHX5; TFDP3; NR4A1; PRDM2; ZNF665; KLF11; HOXC8; POU2F1; POU3F4; MDM4; ZNF214; FOXP3; RORC; FOXN1; ZBTB3; CDX4; IKZF3; MEOX2; LDB1; RAX; GFI1; TSHZ2; CBX7; MAF; ZNF205; HOXD13; ZNF460; HIC1; RBL2; RSF1; AFF3; IKZF2; TBX19; PAX4; ZNF442; ARID3A; ZNF556; NR1I3; KLF15; ZNF132; TRIB3; ZNF180; BNC1; POU5F1B; HMX1; CIR1; NR4A3; POU2F2; DBP; HLF; ZFP2; KLF13; POU3F2; TCF21; SPDEF; MECP2; IRF8; TTF2; ZKSCAN1; ZNF623; THAP9; STAT4; FHL5; ZNF304; ZNF211; ZNF394; KLF3; PBX1; HOXA2; ERCC2; ID1; ESR1; ZNF135; ARNT2; ZNF507; FOSL1; TCEA1; ZNF500; MZF1; CBX2; FOXF2; NEUROD6; ZNF529; ZNF671; CEBPE; SP140L; MAP3K10; PGR; ATN1; SUPT3H; PIR; ZNF675; BRWD1; TOX; CERS6; FOXF1; NANOG; ESRRA; GRHL2; ADRB2; SLC2A4RG; TFEC; SMAD5; MNDA; SAP18; MBD4; ZNF711; TAL1; ZNF85; FOXN3; ZNF93; CREBZF; CNOT3; ZNF331; EN1; HBP1; DLX2; LZTR1; PRMT2; YAP1; PROX1; KDM4C; EHF; HEY1; ZNF350; ZNF222; JUN; ZNF415; ZNF253; HIC2; CREBL2; NR1H4; ZMYM2; FOXL2; SUPT5H; SRCAP; FOXG1; LEF1; ZSCAN31; TCF7; TGFB1; MEIS1; SP140; ZFHX3; TEAD3; MAFF; HTATIP2; GFI1B; MDM2; SALL2; HIPK3; NFE2L3; MYRF; PHF1; BCL11B; HMBOX1; NFAT5; ARID5A; PLAGL1; TRPS1; YBX1; ZNF536; SMARCB1; MEIS2; TBX21; BCL6; EMX2; E2F5; CSDE1; ZNF423; NFIC; SHOX2; IRX5; HOXB2; LITAF; ZNF226; RNF141; WT1; NR1H2; OLIG2; MYT1L; ZSCAN18; GATA1; NKX2-2; KLF1; C1QBP; HIPK1; HEY2; ZNF165; ZNF91; SPIB; TCF4; PEG3; PBXIP1; GTF3A; NKX2-1; ZBTB20; SOX2; KLF4; PAX5; PHOX2B; MECOM; FLI1; HMGA1; KAT6B; ST18; TOB1; TXNIP; RCOR3; TCEB2; CRYM; MEF2C; KLF2; CALR; PITX1; ZMYND8; NR1D2; JUNB; GATA6; OSR2; E2F2; EGR3; SNAI2; MSX1; YBX3; IKZF1; ID3; GATA2
Down-regulation 183 CRK; CCNA2; PAX8; PUF60; SUV39H1; FHL2; NUP62; ECD; HNRNPD; USP22; EED; NFIL3; TRIM32; ATF1; TAF5; UBE2I; TBP; SCAND1; XBP1; CENPF; PCGF2; ADNP; EZH2; NCOA6; HOXA10; TLE1; RFC1; ARID5B; DEK; RBM14; FOXO3; ZNF146; HMGB2; MED1; RNF111; EDF1; SMARCA5; ING2; MYBL2; ERBB2; SNW1; TRIP4; NPAT; RBM39; BRD3; GTF2IRD1; HOXC10; HDAC2; SMAD3; ATF4; MLX; ASXL1; SETD2; BRPF1; MAX; SMARCE1; CDK2; SUZ12; DNAJC2; CRY1; TAF9; ZBTB18; TRIM27; TCERG1; MED27; CNOT1; HOXC6; ZNF263; NELFB; ZNF202; TCF20; ZNF189; ZNF672; BLM; SFPQ; CDK7; MGA; ZBTB24; RBPJ; RBL1; CTR9; TBL1X; PHF20; AATF; HOXA5; PLAGL2; FOXK2; ZNF302; GATAD2A; BRIP1; AFF1; NKX3-1; PTTG1; VEZF1; CDYL; ZNF410; TAF10; JARID2; PPRC1; WHSC1; BMI1; CCNC; STAT5B; GMNN; ZNF148; KAT6A; TLE2; PATZ1; REST; FOXJ3; NR2F2; MAGED1; MED6; PRDM4; NFKB1; RNF138; FOSL2; SMARCD3; BCLAF1; MBD2; RCOR1; CTCF; KDM2A; TGFB1I1; ZBTB11; HIF1A; MED13; CCDC59; SAP30; CNOT6; BAZ1B; ANKRD1; CBX3; YAF2; E2F3; TCF12; PSMC3IP; AGO2; HOXA11; BRCA1; SF1; SOX9; KAT8; ZNF432; NFIB; NRBF2; UBE3A; ITGB3BP; REPIN1; RARA; CTBP2; TRIM28; TFAM; RLF; NPM1; TRIM29; CHD1; MED20; CEBPZ; RAD21; ING3; RREB1; IRF7; TBL1XR1; ELK3; RBBP4; WWC1; COPS2; RUNX1; ELF1; PURA; FOXO1; ENY2; JUND; ZNF281; ZNF131; PBX3; ABL1; NRIP1; KLF6; BASP1; RXRA; THAP11