Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID08121 Cgp-60474 GSE70138 HA1E Human 24h 0.12uM EID0010
Types Number Response transcription factors
Up-regulation 614 EGR1; ZNF264; PRDM14; ZNF391; ZNF154; CHD2; FEZF2; ZNF695; SCAI; ZNF816; ASCL3; NR5A2; SOX5; MAML3; LHX3; ATOH1; GBX1; SSX7; TBR1; EMX1; FOXD3; SPI1; ZNF208; FOXO4; BRDT; SRY; ZNF224; SOX21; SSX3; PDX1; POU6F2; ZNF75D; ZNF223; ZNF701; VENTX; THRB; RFX1; NEUROD2; ZNF682; CIITA; TULP1; ZNF549; SCRT1; FOS; ZKSCAN8; ZNF221; ZNF835; CARF; TP73; SIX6; RFX3; BARX1; ALX4; NFIX; POU2F3; ZNF345; ZIC3; HEYL; SP4; ONECUT1; NEUROD6; ZNF467; ZNF235; ZNF749; HOXC5; PROP1; ZNF814; SHOX; ZFY; ZNF343; SOX18; DOT1L; ZNF471; HNF4G; PRDM9; ESR2; ZNF492; MAK; ZNF440; HSF4; DCC; ZNF215; FOXE3; HES2; NR4A2; PRDM5; ZNF225; HOXB8; FOXB1; ZNF254; HOXB1; NEUROD4; UTF1; ZNF551; HDAC9; ZNF257; HOXA3; SOX14; ZNF771; ZNF362; TEF; SIX3; HIPK2; OVOL2; RBPJL; ASH1L; FOXH1; ZNF180; POU3F3; ETV2; NEUROG3; HIF3A; ZFHX2; IKZF2; PAX7; ZIC4; CRX; PAX1; ZXDC; AIRE; MLLT1; NKX3-2; NFKB2; ZNF780B; AR; ZNF407; MNX1; THRA; CBX7; NR5A1; OVOL1; TBX5; ZNF155; KMT2D; ZFP2; GSC2; ATF7; NEUROG2; ZNF674; NACA2; ZNF484; ZNF136; MEOX2; EPAS1; ZNF80; POU4F3; SOX17; RORA; ZNF507; NHLH2; ZNF550; MDM4; LBX1; ZNF81; TFAP2A; POU1F1; TCEA2; AFF2; SOHLH2; ZIM2; DLX6; TFDP3; MED31; VSX1; TLX3; IRF6; GRIP1; IKZF3; SIX5; HDAC11; SKIL; NR6A1; ZNF688; PRDM1; FOXL1; HOXA2; BNC1; TULP2; HNF1A; SOX13; NR2E1; ZNF304; GCM2; ZNF214; SOX1; NKX6-1; KLF8; TAF6L; EGR4; FOXN1; ZNF117; VHL; RORC; ACTL6B; ZNF8; FOSB; MAPK8IP1; CBX4; ETV3; HOXD3; PAX4; ZBTB39; ZNF157; ZNF778; HDAC5; KLF15; NPAS1; ZNF219; EVX1; RORB; GCM1; ZNF174; HAND2; HESX1; ZBTB7C; ZNF135; BCL11A; LHX6; E2F4; ZSCAN2; CBX8; HOXD12; CBX2; TSHZ2; ZKSCAN4; ZNF671; NKX2-8; ONECUT2; KLF13; ERBB4; PRDM16; SOX30; ZNF528; NEUROG1; HNF1B; SOX3; HAND1; DMRT1; ASCL2; MYT1L; ZNF442; ESRRB; ZNF667; ZFP69B; ZNF675; ZNF606; GTF2A1; HIVEP3; ATF6B; ZNF273; ALX3; ZNF423; DLX5; MSX2; ZBTB7B; ZNF205; SSX1; TAF4B; CRTC1; TBX6; FOXF1; ZNF480; CDX1; NHLH1; NR1H4; SSBP3; GBX2; FOXD2; FOXJ1; LIN28A; NR1I3; MYCL; PRDM12; PAX3; ZNF41; PRDM2; ZNF132; NKX2-5; HOXD13; RNF2; STAT2; CREG1; LHX5; THAP9; L3MBTL1; HOXB5; TAF7L; ZNF234; TONSL; HNF4A; MAP3K10; WHSC1L1; TWIST1; ZNF493; EYA3; CDX4; ZNF711; TBX4; HOXC11; CBFA2T3; FHL5; ZNF557; FOXP3; RAX; ZNF415; TBX10; TBX19; MEF2D; MYEF2; IRF1; WNT4; ATF3; ZNF669; ZNF124; ZNF586; MYT1; AFF3; POU3F4; ZNF544; IRF8; ZNF764; FOXA2; TCEA1; TLX2; KAT2B; REL; ZNF573; SLC2A4RG; ZNF287; ZNF334; TBL1Y; EP300; ZNF460; MYF5; ZNF253; CD3D; VPS72; STAT4; NR4A1; ZNF10; ST18; TCF21; TBX1; HIC1; HOXD1; FOXA1; NFKBIB; NR4A3; PRDM10; ARID3A; ZNF141; EHMT2; ING4; ARRB1; GATA1; ZNF91; ZSCAN32; TLX1; PAX2; CAMTA2; PITX3; ZNF74; LMX1B; SUPT3H; HOXC8; SKI; ZBTB44; TXNIP; PPARA; ZNF506; ZNF613; CDIP1; ZKSCAN3; ZNF556; EN2; SALL2; ZBTB3; RFX2; PHF8; HIC2; ZNF358; ZNF331; ZNF710; TBX21; VGLL1; ZNF611; PEG3; MEIS2; CUX2; PAX6; PITX1; RARG; POU2F1; HBP1; KLF11; ZNF236; ZNF623; CERS6; PRDM13; MYNN; FOXG1; HLF; ELK4; SNAI1; PBXIP1; TFAP2B; ZNF35; PRDM8; SPDEF; GLI1; ZNF500; BCL11B; CREBL2; TUB; MZF1; CIR1; TRIB3; POU4F2; RSF1; HMX1; CIC; ERCC2; FOXC2; SUV39H2; SSBP2; GATA3; MTA2; SRCAP; KDM5C; IKZF4; DBP; ZSCAN9; FOXJ2; BHLHE40; TFDP2; MYCN; HLX; LDB1; CCNT1; TOX; HOXD9; ZNF195; RING1; ZNF562; PFDN5; ZKSCAN7; ETV7; PBX1; ATN1; NEUROD1; THAP10; BARX2; ZNF43; ZNF350; LZTR1; ZNF552; POU5F1B; SHOX2; YBX2; ZNF211; MED25; MAFK; HOXD10; ZNF426; RNF141; MDM2; FOXF2; ZNF536; LHX2; ZNF107; EBF2; CALCOCO1; ESRRA; HEY1; TAF6; TERF1; GFI1; ARNT; HOXB13; MBD4; ZNF222; GFI1B; EN1; DLX4; GRHL2; TAL1; TGFB1; ARNT2; MECOM; MNDA; ZNF329; HOXD11; TAF1; POU3F2; NFIC; EMX2; ZNF770; EYA1; ZBTB20; ZFPM2; SP140; ZNF571; CEBPE; MYRF; ZNF468; MECP2; TSC22D1; NKX2-2; ZNF787; PKNOX2; NFE2L3; CDX2; SOX11; ZBTB32; HDAC4; ARID5A; GLI2; INSM1; PGR; ZNF529; SREBF2; KLF7; NANOG; KLF1; NR1I2; ZNF226; SP140L; TFEC; SAP18; ZNF112; POU2F2; FOXI1; LEF1; DLX2; TCF7L2; SMARCA4; POU2AF1; NR0B1; CRYM; ZNF44; GLI3; CREM; RHOA; HEY2; ZNF184; ISL1; TDRD3; IFI16; RBFOX2; CALR; NR1H2; LITAF; PITX2; ESR1; MAF; ZNF232; FOXL2; ZKSCAN1; SMARCB1; MEF2C; TEAD3; EGR3; ZNF268; CERS4; JUNB; EGR2; PAX5; ID1; BCL6; MED15; MSX1; MKL2; CNOT2; PRRX1; NFAT5; LYL1; ID3; IKZF1; ZSCAN31; BCL3; HMBOX1; CNOT3; HMGA1; NFE2; PLAGL1; WT1; AEBP1; FLI1; PIR; WWP1; ZNF652; NR2F1; SOX2; BACH2; TCF4; E2F5; ETV5; NR1H3; TFAP2C; TRIM22; RFX5; ZFP36L1; KDM5D; HOXB2; KLF4; RXRA; OSR2; E2F2; GATA6; SATB2; GATA2; CREB1; MEIS1; ETV1
Down-regulation 178 CCNA2; NUP62; FHL2; FOXO3; XBP1; CRK; PUF60; TCERG1; ECD; USP22; EED; SUV39H1; HNRNPD; SNW1; DEK; TLE1; PAX8; UBE2I; CENPF; TP53; SMAD3; HMGB2; MYBL2; RNF111; DNAJC2; MBD2; HDAC2; RBM14; TAF9; SUZ12; BCLAF1; ASXL1; NFIL3; SMARCA5; NR2F6; HOXA5; CRY1; PPRC1; RBM39; NCOA6; SCAND1; ERBB2; NPAT; ADNP; MED6; SFPQ; SETD2; ARID4B; PATZ1; ZNF410; ZNF146; ZBTB11; MAX; VEZF1; TRIM29; MTDH; ATF1; CCNC; AATF; BRD8; AGO2; TAF5; COPS5; WHSC1; GTF2IRD1; VGLL4; TRIM32; BRIP1; RBBP4; BRCA1; RFC1; ZBTB1; SP100; CTR9; RAD21; HIF1A; BLM; CHD1; MGA; CNOT6; EZH2; PSIP1; TRIM27; PCGF2; PHF20; BASP1; RNF138; CDK7; KLF6; CTCF; BAZ1A; AFF1; RREB1; CNOT1; BRD3; STAT5B; HOXA10; CBX3; RAN; DR1; BIRC2; REPIN1; ELF1; PHIP; TMF1; ELF5; BMI1; KAT8; SMARCE1; BTAF1; PRDM4; TSC22D2; TGFB1I1; PSPC1; ETS1; NRIP1; FOXJ3; ZBTB18; ZNF84; ZNF189; YWHAB; BCL10; CCDC59; KAT6A; KDM2A; SF1; NELFB; FOXC1; SMARCD3; HSBP1; GATAD2A; RLF; HOXC10; TBL1XR1; ING2; MYBL1; HOXC6; SMAD4; IRF7; CBFB; ZNF302; PTRF; MED1; ZMYM2; ZMIZ1; NFIB; SMARCA2; TBL1X; SIAH2; VDR; EDF1; ITGB3BP; E2F3; PURA; MNAT1; SOX9; SAP30; TLE2; TCF12; FOSL2; RUNX1; CEBPZ; ZNF131; CTBP2; TAF1D; ZBTB38; ZNF281; ZNF217; ILF2; PBX3; DNMT3B; MTF2; NRBF2; ENY2; NR2F2; CHD7; ZBTB16; NR3C1