Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID08120 Cgp-60474 GSE70138 HA1E Human 24h 0.37uM EID0010
Types Number Response transcription factors
Up-regulation 558 EGR1; ZNF224; ZNF264; PRDM14; ZNF551; ZNF606; CEBPD; ZNF667; SCAI; ZNF154; FOS; ZNF701; SOX17; ZNF665; MAML3; EMX1; ZNF75D; ZNF695; ZNF544; SPI1; BCL11A; ZNF391; FEZF2; CIITA; CARF; ZNF136; L3MBTL1; CHD2; POU6F2; ZNF257; ZNF682; SRY; ZNF816; THRB; ASH1L; ZNF688; ZNF440; ZKSCAN8; HEYL; SOX18; ZNF117; TP73; RFX1; NEUROD2; SOX5; ZNF362; ZNF223; DOT1L; PROP1; SSX7; TFAP2A; ZNF345; MAK; ZNF8; ALX4; ZNF304; NEUROG1; ASCL3; VENTX; SCRT1; SSX3; RFX3; NKX6-1; EPAS1; HOXA3; GBX1; ZNF155; SIX6; ZNF586; THRA; ZNF549; ZNF749; ZNF135; NOCT; NFKB2; ZNF471; ZNF235; SOX21; ZSCAN2; ZNF669; TSHZ2; ZNF221; ZKSCAN4; POU2F3; JAK2; ZNF208; WNT4; ZIC3; NR5A2; AIRE; CBX7; ZNF550; NR5A1; E2F4; NR6A1; FOXD3; ZNF611; TWIST1; HLX; ZNF415; PRDM9; ESR2; ZNF174; ZNF254; MDM4; RORA; HOXB1; TCEA2; ZNF780B; PRDM5; PAX1; HMX1; HNF4G; SP4; LHX3; NFIX; NEUROG2; OVOL2; HBP1; NR0B2; ZNF331; BARX1; TBR1; HDAC9; ZNF225; ZNF771; PDX1; ZNF180; BNC1; EP300; ING4; HIPK2; HSF4; ZNF562; NEUROG3; ONECUT1; ZNF93; ATF7; NEUROD4; TULP1; TBX6; MED12; PEG3; GBX2; ZFHX2; ATOH1; EVX1; PRDM12; NHLH2; ZNF814; HIC2; HLF; CRX; MLLT1; LIN28A; MDM2; ZNF343; HOXD3; HOXC5; ZNF467; IKZF2; NPAS1; RBPJL; ZNF500; GRIP1; WHSC1L1; ZNF273; NKX3-2; ZNF81; CD3D; ZNF219; HDAC5; TBX5; ZFP69B; FOXB1; ZSCAN31; HIF3A; TEF; POU3F3; FOXE3; TBX1; ZNF835; GSC2; TAF1; ZNF197; ZNF778; ZNF205; ONECUT2; ZNF43; HNF4A; REL; AR; HES2; HAND1; BRDT; SOX3; ZNF91; MYCL; ZNF652; VHL; ETV3; TLX3; ZNF492; ZNF329; ZNF623; SUPT3H; NR4A2; EZH1; VGLL1; ZFP2; DCC; IRF1; ZNF334; FHL5; ZNF493; IRF6; CDX4; ZNF141; HOXD1; FOXA1; HESX1; ZBTB7B; KLF8; ERBB4; ZNF556; ZSCAN32; ESRRB; ZNF10; CCNT1; RORB; POU4F3; SOX13; TAF4B; KMT2D; ZNF674; ZNF423; FOXJ1; E4F1; ETV2; ZNF671; KDM4C; CBX8; ZNF132; IRF8; ZNF214; BRWD1; ZNF573; MEF2D; TCEA1; ZNF80; FOXL1; ZBED2; CDIP1; SOX14; ZNF484; NFATC4; ZNF710; TONSL; CBX4; ZNF44; ZNF350; KDM5C; SKIL; TAF6L; ZNF112; ZXDC; ZNF407; ZNF711; LDB1; SIX5; LBX1; ZFPM2; KLF13; DMRT1; FOXH1; GTF2A1; RARG; SOX1; CALR; TLX1; ZKSCAN3; HOXB8; HOXD12; TCF7L2; MYT1; CERS6; NEUROD6; CEBPE; PRRX1; TBX10; ZNF506; ACTL6B; CBFA2T3; RBL2; PRDM2; GCM2; ZNF74; KLF15; JUP; PBX2; ZXDB; MNX1; ZIM2; MEOX2; SSBP3; DLX6; ZNF124; TFDP3; TEAD3; FOXN1; ZNF442; AFF2; MXD4; TLX2; PRDM16; OVOL1; ZNF234; ZNF426; HAND2; MED25; ZNF157; NKX2-8; ARID3A; MYNN; RFX2; CIR1; ZNF287; HIC1; CBX2; ZNF232; SLC2A4RG; THAP9; ZNF41; SALL2; AFF3; ZNF134; ARHGAP35; MED31; RORC; PAX4; UTF1; SIX3; POU1F1; NHLH1; LHX6; ARNT2; ATN1; HOXD13; RSF1; DLX4; MSX2; MAP3K10; PAX3; KAT2B; HOXC8; EHMT2; SOX12; ZNF215; MYEF2; POU3F4; ZNF675; SRCAP; ZBTB44; MEIS2; TUB; IKZF4; ZSCAN9; FOXP3; ZNF358; LMX1B; MNDA; LHX5; FOXA2; ZNF222; ZNF85; NEUROD1; ZNF211; TCF21; ZFP30; MYCN; MAPK8IP1; RAX; EN1; SPDEF; CREG1; ZBTB3; SOHLH2; HDAC11; ZKSCAN7; HOXA2; ZNF557; NFKBIB; NR1H4; INSR; ASCL2; HOXC4; MECP2; PAX6; MYRF; PRDM10; MAF; IKZF1; PRDM1; RXRG; CRTC1; ZNF177; ZNF507; TAF1A; TRIB3; IKZF3; STAT2; NR1I2; ZNF253; NR1I3; NR2E1; SP140L; NANOG; SHOX2; ESR1; FOSB; PLAGL1; PBX1; LZTR1; CUX2; SMARCB1; WT1; MZF1; C1QBP; ARL2BP; POU2F2; RING1; HHEX; CERS4; ZNF268; ZNF195; ID1; TBX21; NR4A3; SUPT4H1; PHOX2A; ZSCAN18; TAL1; SKI; HIPK1; ETV5; ZNF770; AEBP1; ZNF528; ZNF529; HOXB13; CTNNB1; EMX2; ZNF354A; KLF11; ARRB1; GATA1; NR2F1; CALCOCO1; CRYM; NR2C1; TBX19; ZNF654; HMGA2; TCEB2; FUBP1; DBP; GFI1; SOX15; FOXF1; NR1H2; ZBTB20; IRF3; ZNF83; CNOT3; DLX5; NOC2L; ARID4A; BNC2; ARID5A; ZNF239; PNRC1; MYT1L; ST18; ZNF532; HIRA; NR4A1; FOXF2; HOXB5; GATA6; ZNF580; EN2; TP63; JUNB; ZNF107; GRHL2; PBXIP1; TXNIP; TGIF2; SSX1; NFAT5; TGFB1; TGIF1; STAT4; CEBPA; SPIB; VPS72; IRF9; GFI1B; CREM; CREBZF; ZHX2; HEY1; E2F5; SNAI2; TFEC; BACH2; LEF1; NFIC; CSDE1; ZFP36L2; KLF1; FOXN3; TCF4; ID3; ZNF22; ZNF160; PHOX2B; HEY2; NR0B1; TOX; NCOA3; NFE2; WWTR1; TCF7; PITX1; ATF3; TFAP2C; AHR; CITED2; ZFP36L1; HMGA1; GTF3A; NKX2-2; OSR2; INSM1; BCL3; PAX5; MECOM; HOXB2; ZNF721; CREB1; MEF2C; EGR3; SOX2; SOX11; MEIS1; GATA2; E2F2
Down-regulation 193 FHL2; CRK; CCNA2; NUP62; PAX8; PUF60; ECD; HNRNPD; NFKBIA; SUV39H1; HOXA10; EED; FOXO3; FOSL1; EZH2; CENPF; CTR9; TBP; SMARCA5; TCERG1; TRIM32; TLE1; NFIL3; RNF111; RBM14; XBP1; SMAD2; MYC; HOXA5; MBD2; NPAT; SMAD3; USP22; NCOA6; ADNP; ATF1; CRY1; SNW1; ZNF146; ASXL1; VEZF1; DNAJC2; UBE2I; HDAC2; REST; PHF20; TP53; BASP1; CDK2; TRIP4; JARID2; SETD2; TAF9; BLM; CBX3; ZNF143; DEK; PURA; ARID4B; ZBTB18; BRPF1; PPRC1; ING2; BRD3; SOX4; PCGF2; NCOA4; TRIM27; FOSL2; NELFB; NFKB1; ITGB3BP; BCLAF1; KLF6; TAF10; PATZ1; EDF1; BMI1; TCF12; KDM2A; CNOT1; HOXC6; REPIN1; ZMYM2; FOXJ3; MED6; ZMIZ2; KAT7; CHD8; AATF; ZNF672; ETS1; RNF4; TBL1X; GTF2IRD1; RBBP4; MLX; ZNF410; NR2F2; BAZ1B; BRD8; SIX1; YAF2; SMARCD3; NCOR2; KAT5; MED1; RUNX1; PREB; BHLHE40; MTDH; SFPQ; CXXC1; ELK1; DNAJC1; TSC22D2; ANKRD1; TBPL1; CDC5L; BATF3; ELK3; AFF1; WHSC1; SMAD7; RNF138; ZBTB1; SETD3; PTTG1; SCAND1; ZBTB11; FOXC1; RELA; MAX; IRF7; CDK7; MAGED1; DEAF1; HOXC10; GATAD2A; CDYL; BCL10; HOXA11; SMARCE1; ENO1; RARA; MEF2A; CTCF; BIRC2; DDX17; BRIP1; NCOA1; SF1; CCNC; SSRP1; NKX3-1; NRIP1; RREB1; ZNF148; SAP30; VGLL4; BCOR; ELF1; CEBPZ; BRCA1; PBX3; MAFB; ZBTB38; NRBF2; SIAH2; CTBP2; NAB1; NPM1; E2F3; YWHAB; RCOR1; TFCP2L1; HOXB7; DNMT3B; FOXD1; RNF6; TRIM29; FLNA; MYBL1; SIX2; TRIM16; RBBP8; TRIP6; HTATIP2; BTG1; ABL1; KLF10; SOX9; NR3C1