Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID08105 Pf-562271 GSE70138 HA1E Human 24h 10uM EID0010
Types Number Response transcription factors
Up-regulation 572 CEBPD; EGR1; NHLH2; ZNF264; SPI1; PRDM14; SRY; FOSB; ZNF391; TP73; FOXO4; SOX21; ATOH1; NR4A2; ZNF778; NFKB2; NEUROD4; EMX1; CHD2; ZXDC; POU6F2; ALX4; ZBTB48; SOX5; TAF4B; RFX1; HOXB1; ZNF154; ZNF695; ZNF224; NEUROG2; FOXD3; ZNF440; PRDM2; NR4A3; MAK; MYT1; ASCL3; NEUROD1; ZNF492; SOX1; AR; TWIST1; NEUROD2; FEZF2; TBX6; RBPJL; ZNF682; MAML3; TULP1; ATF6B; TBR1; ZIC3; SCRT1; PBX2; ZNF467; POU4F2; HES2; ZNF136; NKX6-1; PDX1; ZNF701; HLX; SOX14; L3MBTL1; SSX3; SCAI; GBX2; HDAC5; ZNF331; PAX7; NEUROD6; HOXD3; ZNF117; HIF3A; ZNF667; DOT1L; ZNF549; MLLT1; HOXB8; SOX18; ONECUT1; SHOX; BCL6; FOS; FOXL1; NFIX; PRDM9; BCL11A; THRA; TBX5; RFX3; TBX1; ZNF551; REL; NEUROG3; HOXA3; ZIC4; SSX7; BRDT; PAX1; CREG1; NOCT; HAND1; ZNF223; ACTL6B; MAF; RNF2; GBX1; DMRT1; STAT2; ZNF749; ZFY; ZNF208; ZNF257; ZNF550; LHX3; ZFPM2; ZNF362; CRX; ATF7; NEUROG1; IRF1; NR5A2; NKX3-2; ZNF669; NHLH1; ZNF442; CSDE1; NR5A1; ZNF235; THAP10; TEF; PRDM5; VENTX; GSC2; NACA2; ZNF10; HOXC8; FOXB1; POU2F3; ZFP69B; ZFHX2; GCM1; NFKBIB; LDB1; HESX1; ZNF606; POU3F3; TLX3; LBX1; HNF4G; DCC; ESRRB; FOXH1; TFDP3; ZNF688; CD3D; TAF1C; HOXA6; MED12; NPAS1; CARF; ESR2; THRB; SHOX2; IKZF3; PROP1; FOXE3; HEYL; MYEF2; TULP2; MYC; OVOL2; INSM1; UTF1; ZNF221; ZNF215; ZNF771; CIR1; SIX6; HAND2; PAX3; ZNF532; ZNF343; ETV2; MNX1; EN2; MAPK8IP1; ZNF471; SIX3; RORB; TFDP2; ZNF814; ZIM2; TLX2; ZKSCAN4; WHSC1L1; CDX4; VHL; MSX2; HSF4; GCM2; DLX4; ZNF141; HOXD12; PRDM16; ZNF407; ZNF75D; ZNF493; ZNF81; KMT2D; PHF8; GRIP1; HIPK2; ZNF345; ZKSCAN8; DLX6; POU1F1; CDX1; ZNF674; SP4; MYF5; ZNF536; ZNF80; DLX5; ZNF573; MYNN; FOXD2; ZNF157; TONSL; ARID5A; ZNF273; ZNF358; ZNF214; FOXP3; ETV3; ZNF460; ZNF611; ZNF556; GFI1; POU2AF1; ZNF764; CBX7; ZNF225; LHX5; MEF2D; EGR4; ATF3; KLF8; ZNF304; TBX10; LZTR1; ZSCAN2; ZNF780B; ZBTB7C; MZF1; VSX1; WNT4; MYBBP1A; ETS2; PHOX2A; CREBL2; ZNF44; ONECUT2; NR0B1; PRDM1; ZFP2; BARX1; HDAC11; NR4A1; POU4F3; ZBED2; SIX5; POU3F4; ZNF155; ZNF222; USP16; ZNF132; MDM2; NKX2-8; MAFF; PEG3; SUPT3H; ZNF544; HOXC5; RSF1; CIITA; ASCL2; RORC; INSR; TCEA2; PAX4; PBX1; KLF7; ZNF8; ZNF557; KLF15; SCMH1; FOXA1; LHX6; IKZF2; BNC1; GCFC2; EHMT2; EYA3; AIRE; LMX1B; NKX2-5; OVOL1; MYT1L; ASH1L; ZNF423; TBX19; EBF2; EP300; ZNF41; HIVEP3; PPARA; CUX2; NR1H4; SOX17; PRDM12; TFAP2B; ALX3; TFAP2A; MED31; HDAC9; ZFP37; JUN; ZNF14; ZBTB44; EPAS1; THAP9; CDIP1; PLAGL1; MXI1; ARID3A; KLF13; HEY1; HIC1; RAX; ZNF816; ZSCAN12; HIPK1; MED25; TAF6L; HOXD13; ZNF529; ZNF205; HOXA2; ZNF562; HNF4A; AFF3; CDX2; MNDA; ZNF710; MAP3K10; CSDC2; HOXD9; MDM4; SIM1; CBX2; CREM; FOXI1; HBP1; LIN28A; SSBP3; POU2F2; ZBTB17; SNAI1; ZNF623; ZSCAN9; IRF6; OLIG2; FOXC2; TAF7L; IFNB1; ZNF91; RFX2; SP140; RORA; ZNF334; ZBTB3; FUBP1; ZNF415; SKIL; TFEC; NKX2-2; ZNF835; ZNF426; ZNF254; BCL11B; SUPT4H1; ZBTB32; TLX1; ZNF528; NR1I3; ZNF711; PHF1; TRAK1; HOXC4; ZNF507; TGS1; NR1I2; POU5F1B; FOXL2; BHLHE40; HMGA2; FHL5; ZNF219; VGLL1; CREB5; CBX4; SIN3B; CERS6; FOXA2; ZBTB7B; POU3F2; SPDEF; EGR3; MEOX2; YBX2; RXRG; SSX1; IRF8; RARG; MAFK; CALCOCO1; ZNF787; HOXD10; RELB; THRAP3; FOXJ1; SOX3; ZNF195; TBX21; CBFA2T3; ZKSCAN7; NFATC1; NFE2L3; TGFB1; ZNF813; SALL2; CAMTA1; ZNF354A; LZTS1; MTA2; FOXF1; ZNF671; SOHLH2; LEF1; NFIC; ZNF112; PKNOX2; LITAF; DLX2; SMAD6; CAMTA2; SKI; HOXB13; ZSCAN18; MECOM; ZNF394; DBP; HMBOX1; ARRB1; ZNF770; SLC2A4RG; ATN1; HOXB5; ST18; ESR1; TDP2; NOC2L; ZNF350; FEV; MYCN; PNRC1; CNOT3; IRF4; STAT4; ZNF268; ZBTB43; ZNF124; PIR; ARNT2; NR2E1; TSC22D3; SOX11; KAT2B; ERBB4; ZNF721; MXD1; MYRF; HLF; HMGN3; MYCL; HMGA1; AES; RUNX3; NANOG; TCF4; MSX1; HIC2; KAT6B; ZNF43; TFEB; ZNF107; CTNNB1; ZNF580; PHOX2B; NR1H3; BNC2; FLI1; KLF11; HLTF; PAX6; MSC; ZNF165; TSC22D1; EMX2; SNAI2; PGR; TERF1; SPIB; EYA1; MEF2C; CALR; GRHL2; EGR2; RBFOX2; ZNF160; BCL3; TCF7; FOXF2; PAX5; GTF3A; FOXN3; JUNB; PBXIP1; MTF2; CHD7; SMARCA1; LMCD1; FOXG1; STAT3; BHLHE41; ID3; NR1H2; MAFB; YBX3; ZEB1; KLF4; KLF2; IKZF1; E2F5; MEIS2; ISL1; ID1; FOXO1; TCF21; KLF9; PITX1; AEBP1; TRIM22; TXNIP; WT1; OSR2; SOX2; E2F2; GATA2
Down-regulation 191 CCNA2; TLE1; PUF60; FHL2; PAX8; EED; FOXO3; CENPF; HNRNPD; CRK; TP53; SUV39H1; XBP1; NCOA6; ECD; VEZF1; ADNP; ATF1; MBD2; NR2F6; MYBL2; CDK7; NUP62; HDAC2; MED27; HOXA10; SCAND1; SOX4; SMARCA5; DEK; MED1; NPAT; CCNC; CNOT1; REST; CBX3; ZNF146; PRPF6; SNW1; UBE2I; TRIM27; TRIM32; WHSC1; FOXK2; RBM14; USP22; ZNF672; BRD3; RNF111; HOXB7; CHD8; YWHAB; BLM; KAT7; BRIP1; SMARCE1; ERBB2; ZNF131; GTF2IRD1; RAD21; SUZ12; TAF5; RFC1; ARID5B; APEX1; AATF; HMGB2; ING2; CTCF; SMAD4; ZBTB24; ASXL1; TAF4; GATAD2A; SAP30; SMAD1; NELFB; FOSL1; PCGF2; ZNF143; TBL1XR1; HIF1A; BRPF1; PTRF; TCF20; TRIM29; CEBPZ; ZNF263; HOXA5; MED6; URI1; EDF1; RNF4; FOXC1; RCOR1; PAWR; RAN; MED20; TAF9; YAF2; NRIP1; ZNF148; CCDC59; KMT2A; SFPQ; RBPMS; MED21; SP3; MYBL1; SSRP1; RBBP7; BCLAF1; ELF5; FOXM1; TBL1X; ATF4; MED13; BRD7; MAX; HMGB1; NPM1; ILF2; ZNF302; BRCA1; CDYL; MLXIP; PATZ1; CRY1; DNAJC2; ID4; RBBP4; ARID4B; WWC1; ZNF410; KLF10; ZFP36L1; PHF20; ZNF217; PHIP; ZNF266; BAZ1B; HOXC6; IRF7; CEBPG; PTTG1; CTBP2; RNF138; HOXA11; RREB1; ITGB3BP; SF1; CENPB; ZBTB1; SMAD3; NCOA4; BATF3; FLNA; ZMYM2; TEAD4; NKX3-1; PSIP1; BAZ1A; SMARCD3; NR2F2; NFYB; COPS5; BMI1; TGFB1I1; PQBP1; KAT8; ZBTB18; RUNX1; HMGB3; ELK3; PURA; SOX9; NFATC3; DNMT3B; CITED2; KLF6; HOXC10; TOB1; TRIM16; FOXD1; TLE4; RXRA; MNAT1; BTG1; HOXB6; NR3C1; THAP11