Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID08101 Mk-2206 GSE70138 HA1E Human 24h 1.11uM EID0010
Types Number Response transcription factors
Up-regulation 106 POU2F1; NFX1; EZH1; HSF4; HDAC5; BACH1; CDK8; DLX5; IRF2; STAT2; KDM5C; CNOT2; TGS1; SOHLH2; HBP1; TTF1; ZNF516; ZNF175; HMGB2; PCGF3; SSX1; SIM1; BPTF; LHX3; CEBPB; MDM2; ZIC3; MNAT1; ZNF711; MAGED1; MED14; CDC5L; HMGXB4; ZNF415; EWSR1; CTR9; ZNF264; PPP1R13L; SERTAD2; JARID2; BRF2; DLX2; TERF1; MSX1; ZNF574; ZNF107; MEOX2; LPIN2; MED24; ZNF232; DNMT3B; TOPORS; CBX7; CAMTA1; SMARCD3; TFEB; TGIF1; RNF141; MEF2A; ATF7IP; YEATS4; DBP; PBX1; ZNF529; NFAT5; HEY2; FOXG1; REPIN1; TFEC; STAT6; NR0B1; SATB2; SALL1; RXRA; TBL1X; PBXIP1; FOXA2; ARID1A; KAT6B; RBPMS; ZMYND8; EYA2; IRF6; TRIM16; GATA6; ZNF83; OSR2; MNDA; CREB3L2; FLI1; RBFOX2; CITED2; MECOM; ZBTB16; NKX2-2; ZHX2; MAFB; CALR; IFI16; TCF4; YBX3; HEY1; TXNIP; TRIP6; EMX2; ABL1
Down-regulation 49 BRD4; HDAC3; CRY1; ZNF148; CNBP; DEK; ZFP36L1; RNF138; SAP130; ZNF593; ZBED2; VEZF1; ATF1; CBX3; MTDH; CCNH; IRX5; FLNA; PTTG1; SP100; PTRF; TGIF2; STAT3; IRF4; AHR; CHD1; FOSL2; ZBTB38; ZNF91; BRD2; BBX; KLF10; DACH1; HTATIP2; BIRC2; SFPQ; IRF7; CTBP2; EHF; THAP11; NFIB; HOXB6; HHEX; BHLHE41; TGFB1; CREB1; TOB1; ATF3; WT1