Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID08099 Mk-2206 GSE70138 HA1E Human 24h 10uM EID0010
Types Number Response transcription factors
Up-regulation 75 HMGA2; CEBPD; TSC22D1; ZNF688; TCEA2; ING4; HBP1; PCGF2; CBX7; SREBF2; THAP10; MZF1; CALCOCO1; PEX14; NKX3-2; ZNF623; HIPK2; FOXG1; CREBL2; ZNF131; INSR; ZNF226; ZNF24; NONO; ETV5; AR; SALL1; HMGA1; SALL2; TAF6; ARNT2; NR1H4; RORA; TRIB3; IFI16; ZMIZ2; CEBPB; FOXA1; KLF11; ZNF467; MNDA; REPIN1; MAFB; FOXD1; MITF; HDAC9; NR1H3; NR2C1; ATN1; RBFOX2; IRF8; AEBP1; GATA2; ZNF217; ZNF160; HOXB2; CUX2; ELK3; FLI1; TGIF1; ERBB4; ZNF721; ZFP36L2; TCF7; AHR; ST18; HEY1; INSM1; SOX11; ESR1; LEF1; MEIS2; KDM5D; YBX3; THAP11
Down-regulation 47 NFKBIA; MYBL2; MYCBP; KMT5A; PIAS2; EGR1; PTRF; STAT5B; ELF5; VEZF1; TCF3; FLNA; NFIL3; WWC1; ZNF652; CHD7; ZBTB1; SMAD3; STAT3; PDLIM1; FOXC1; RAN; REL; SFPQ; SERTAD2; ID4; YWHAB; CREB3L1; FOXO1; SOX10; ETS1; NFATC3; KLF5; ATF3; LITAF; CUX1; TLE4; NFE2; EHF; PAX5; SNAI2; PITX1; BBX; MYBL1; PBX3; OSR2; RELB