Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID08090 Osi-027 GSE70138 HA1E Human 24h 0.37uM EID0010
Types Number Response transcription factors
Up-regulation 110 NFATC4; HES1; MDM4; ZNF623; ZNF440; ZNF257; TBX1; WDHD1; ZNF236; L3MBTL1; ZNF695; ZNF492; TGFB1I1; ZNF141; ZNF165; ZNF493; BRWD1; ZNF682; ZNF764; BNC1; AFF2; ZNF180; ZNF254; ZNF667; ZNF117; SCAI; ZNF674; FHL5; ZNF214; CARF; ARID5B; SOX18; ZNF345; ZNF551; ERG; PLAG1; ZNF675; E2F8; MYB; POU1F1; BRCA2; STAT2; RSF1; TLE2; HMGB3; MDM2; HHEX; ZBED2; POU2AF1; CDK9; ELF3; VGLL1; PAWR; PBXIP1; SOX4; HOXB5; NEUROD1; PPP1R13L; PGR; PRMT2; SOX17; BCL6; HOXB7; ZNF107; KLF11; INSR; IRX5; ZNF711; HDAC9; ZNF516; KLF7; ZNF43; IRF6; ZNF529; KLF10; HOXB2; POU4F1; INSM1; AEBP1; ETS2; WWP1; RBBP4; TCF7L1; FLI1; PAX5; TLE4; TAF1D; HEY2; TCEB2; LEF1; HOXB6; ZBTB18; IFI16; PBX1; ZNF217; RCOR3; ZNF83; NFE2L3; BACH2; YBX3; PLAGL1; BRCA1; CTNNB1; FOXO1; ESR1; ZNF91; EHF; TOX; WT1; EMX2
Down-regulation 43 TSC22D1; NFRKB; NCOA6; PFDN5; RBPJ; DNAJC1; TULP4; STAT1; ZNF331; CEBPB; BMI1; YWHAB; SMARCA2; KLF9; NCOA4; CCNE1; ABL1; BANP; TOX3; LITAF; FOXD1; MYCL; ID2; ARID1A; NKX3-1; RAN; BASP1; JUNB; STAT4; ZFP36L2; FOSB; GTF3A; EYA1; NFATC3; SIX2; CREB3L2; RBFOX2; NR2F2; AFF1; THAP11; ID1; GATA2; TBX2