Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID08069 Saracatinib GSE70138 HA1E Human 24h 10uM EID0010
Types Number Response transcription factors
Up-regulation 87 CEBPD; TCFL5; PAX8; YBX2; HDAC5; HDAC6; CBX7; MNT; TRIM29; TCEA2; EZH2; IRF6; IRF1; SMARCD3; NR1H3; ZNF219; ZNF334; IFI16; E2F2; ZNF337; GLI3; IRF9; HMG20B; MDFI; TTF2; ZBED2; STAT2; IRF3; SREBF2; PRDM1; RUNX3; CERS4; DNMT3B; CBX6; ZNF394; SP110; SREBF1; ZNF226; TP63; MAGED1; YEATS4; STAT6; PIR; PLAG1; UBE2L3; MYRF; ARID4B; STAT1; ZKSCAN1; DBP; NAB1; CARHSP1; ZBED4; SALL2; SOX15; BCL6; SSX1; IRF8; RHOA; BHLHE41; SMARCA1; HOXD1; LITAF; TXNIP; KDM5D; TRIM22; ZNF165; ELF3; PEG3; ZNF529; TERF1; CD3D; ATF7IP; NFE2L3; MNDA; STAT4; NR0B1; MAFB; ZNF589; TRIP6; KLF5; TSC22D1; IRF7; RBBP8; EYA2; EGR3; PSIP1
Down-regulation 95 LOXL2; CCNC; TULP4; JUN; ZNF93; CCNH; HNRNPD; XBP1; KLF2; USP22; HIVEP2; TFDP1; FOXK2; BRD3; ETS1; TBPL1; PRRX1; KLF3; ZNF593; ID2; KLF7; LMCD1; RFX5; ZMIZ1; SIM2; CDYL; DEK; HIF1A; CREB5; ZFHX3; EDF1; SIX1; TFDP2; YBX1; EGR1; FOSB; ZNF512B; FOSL2; CDK9; IRX5; GATAD2A; CEBPB; CITED2; ZBTB18; HEY1; C1QBP; SHOX2; FOS; ZNF423; HHEX; APEX1; CHD1; HMBOX1; HMGN3; BRD7; TOX; NR2F2; CREBZF; RARA; MYBL1; ETS2; DACH1; SFPQ; TWIST1; ZNF652; BHLHE40; ID1; RAN; CBFB; BMI1; RYBP; CREB3L1; HMGB1; ABL1; ELF5; RCOR3; TBL1XR1; HOXC6; ELF1; NR4A2; ZEB1; ZNF160; THAP11; ZNF721; HOXB6; FOXC1; SOX9; ID3; ATF3; FOXF2; AHR; CREB1; ARNT2; TOB1; NR3C1