Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID08063 Bms-345541 GSE70138 HA1E Human 24h 10uM EID0010
Types Number Response transcription factors
Up-regulation 625 FOS; EGR1; CEBPD; SPI1; PRDM14; ZNF224; FEZF2; RBPJL; ZNF154; CHD2; ZNF682; POU6F2; FOSB; EMX1; TP73; MAML3; NR5A2; ZNF551; SCAI; HDAC9; SRY; PRDM9; SOX21; MAK; ZNF701; ZNF235; SOX17; NR4A2; THRA; TULP1; TBX6; ZNF440; VENTX; PDX1; ZNF345; POU2F3; ZNF362; NEUROD2; ZXDC; ZNF155; ZNF75D; ZNF695; ZKSCAN4; SCRT1; SOX18; ZNF391; RFX3; GRIP1; TCEA2; HSF4; WNT4; NR6A1; BARX1; MYCL; HNF4G; ZNF257; HOXB8; ZNF549; ATOH1; NEUROG2; FOXD3; BCL11A; HOXB1; NKX6-1; HIF3A; ALX4; ZNF174; NFIX; HOXC5; ERBB4; ETV3; CRX; RFX1; ZNF471; GBX2; TCEA1; TBR1; ZIC4; E2F4; POU4F3; DOT1L; ZNF749; JAK2; HNF1A; ONECUT2; ZNF117; ETV2; FOXE3; NKX3-2; CARF; SOX1; VSX1; ZNF221; TLX3; CIITA; ZNF606; THRB; ZNF816; SOX14; GBX1; EVX1; TONSL; SSX7; ZNF264; NFKB2; TFAP2A; ZNF467; ZIC3; NEUROG3; ACTL6B; HOXB5; SIX6; AIRE; ZFP2; POU3F3; ZNF254; FOXL1; ZNF225; MDM2; LBX1; ZNF223; ZNF492; IRF8; LHX3; BRDT; ZNF814; ZNF669; HOXD3; NEUROD4; ZNF573; ASH1L; HEYL; ATF6B; FOXB1; ZNF274; ASCL3; ZNF80; OVOL2; HOXA3; VPS72; ZNF415; TRIB3; BNC1; ZNF334; ATF3; ESRRB; IKZF2; REL; ZNF180; ZNF710; ATF7; MLLT1; UTF1; ZNF219; ZNF407; ONECUT1; VHL; TULP2; KLF8; ZNF544; ZNF215; ZXDB; WHSC1L1; PAX7; TCF21; MNX1; TAF4B; NR1H4; MDM4; ZNF232; GSC2; TBX1; VGLL1; ZKSCAN8; RARG; CBFA2T3; HOXA6; HOXD12; ZNF771; SP4; ESR2; JUN; NPAS1; ZBTB7C; ZNF157; ZNF343; NEUROD6; ZNF423; TBX10; HMX1; ZNF304; MNDA; FOXH1; TFDP3; TBX5; NHLH2; PAX1; SHOX; ZNF81; POU3F4; ZNF674; CBX4; MAPK8IP1; NR0B2; ZNF208; MEIS2; E4F1; ZNF778; ING4; NR2C2; CDX4; DMRT1; SIX5; PAX4; MYEF2; ZNF442; PRDM2; TEF; ZNF557; ZNF214; ZBTB48; AR; ZFP69B; GCM1; SSX3; PRDM16; ZNF41; ZNF550; PROP1; EHMT2; HOXD13; GCM2; AFF3; SIX3; NOCT; TLX2; ZNF141; ZNF197; ZNF780B; TWIST1; PRDM5; RORB; PRDM10; MSX2; ZNF667; ZNF675; POU1F1; DLX6; HLX; ZNF234; RUNX2; DCC; NACA2; PRDM12; ZFHX2; KDM4C; NFATC4; HAND2; KLF15; ZSCAN2; NFKBIB; NR5A1; ZNF623; FOXJ1; ASCL2; HAND1; TBX4; CDX1; TBL1Y; HHEX; ZNF135; ZNF688; HOXB13; ZNF613; TAF6L; HNF4A; ZNF484; TAF1C; CBX8; L3MBTL1; PITX3; HES2; ZNF10; ZIM2; TLX1; MYF5; ZNF34; GTF2A1; ZNF136; KAT2B; DLX2; ALX3; NR2E1; HOXA2; NEUROD1; ZNF536; RAX; HOXB3; ZFY; RORC; NHLH1; ZNF85; ZNF500; GRHL2; RSF1; IRF6; ZBTB3; NKX2-5; NR4A1; OVOL1; DLX5; NEUROG1; NKX2-8; PBX2; SSBP3; GFI1; ZKSCAN3; ZNF493; ZNF507; IKZF3; SOX5; ZNF132; ZNF711; LHX5; ARNT2; ZBTB44; TBX19; POU4F2; ZNF33B; PPARA; PAX3; ZNF287; CBX2; ZNF671; RFXAP; FHL5; MEOX2; DLX4; ZNF43; FOXP3; ZNF35; C1QBP; MED31; PEX14; FOXI1; MYT1; ZNF460; HIPK2; ZNF205; SOX3; POU6F1; LIN28A; SOX13; RUVBL1; PEG3; THAP9; CUX2; TTF2; BARX2; ZNF273; ZNF107; FOXA1; FOXD2; IKZF4; FOXN1; PAX2; PAX6; CDIP1; ZNF91; HES1; ZFP37; HOXD1; POU5F1B; WDR77; ZNF480; HESX1; ZBTB7B; LZTR1; AFF2; SOX30; HDAC11; MTA2; THAP3; ETV7; AEBP1; THAP10; HOXB2; HDAC5; MED25; SOHLH2; PNRC1; LDB1; BHLHE41; SKIL; NFE2L3; MAP3K10; ZNF44; PRDM8; CD3D; ST18; WT1; MBD4; ZFPM2; CRYM; ZNF350; POU3F2; SPDEF; LHX6; ZSCAN9; TGIF2; CEBPE; CREBL2; TUB; CRTC1; SALL2; ZNF74; ZNF8; SNAPC4; MYRF; ZNF506; EYA3; EPAS1; SKI; FOXF2; ZNF835; FOXF1; PRDM1; MZF1; DYRK1B; ZNF611; ZNF770; HIRA; LMO1; ISL1; VAX2; TSHZ2; LMX1B; INSR; CIR1; NANOG; PAXBP1; CERS4; EN1; ZNF93; LHX1; HOXA1; MAFK; CAMTA2; NR4A3; RXRG; SRCAP; HOXC4; NOC2L; SLC2A4RG; IRF1; ZNF444; CBX7; FOXJ2; SHOX2; ETV6; HOXC8; SOX12; TERF1; BAZ2A; ZNF556; ZNF562; ZNF665; HIC1; LEF1; ZKSCAN7; MXD1; ZNF195; PITX1; TAF7L; DBP; POU2F2; ZNF787; ZNF580; EP300; MYF6; ZNF529; ATN1; NR1I3; ZNF329; HOXB6; SNAI1; IRX5; KLF13; ZNF419; PBX1; ELF3; SMARCB1; FOXA2; ID3; MECP2; CBL; ID1; ZNF532; TFEB; ARRB1; PEX2; ZNF331; ZNF768; ZNF211; MXI1; SP140; CNOT3; ARL2BP; NR1I2; ESR1; TDP2; ZNF253; PKNOX2; NFE2L2; EGR4; PRRX1; CREM; CREG1; MYT1L; MYB; ZBED2; GLI2; TBX21; OSR2; PIAS1; ZSCAN16; GLI3; ZNF654; IRF3; NCOA2; KLF1; JUNB; HMGA1; BRF2; EN2; TRIM22; ZNF124; GFI1B; BACH2; ZFHX3; CALCOCO1; CAMTA1; MECOM; ZSCAN31; ZNF394; VDR; NFATC1; TGFB1; SOX11; LYL1; ZNF268; ZNF226; ZBTB20; CEBPB; RING1; EGR2; INSM1; ID4; TAF6; TFEC; CERS6; HEY2; YEATS4; STAT4; PAX5; TAL1; EMX2; POU4F1; CREBZF; SMARCA4; OLIG2; SPIB; ZNF652; HIC2; NR2F1; SP140L; ZNF516; TBX3; HMBOX1; TULP3; PLAGL1; TEAD3; JUP; ZNF184; RFX5; PBXIP1; NR1H2; EYA1; FLI1; GATA1; POU2AF1; MYCN; E2F5; PHOX2B; FOXL2; ARID1A; GTF2I; MSX1; CALR; FOXG1; ZNF589; SNAI2; ZSCAN18; CTNNB1; MYBL1; BCL6; NR0B1; HLF; NFE2; SOX2; MEF2C; YBX3; GATA6; HEY1; ZFP36L2; TOX; ZHX2; DACH1; TOX3; TCF4; CEBPA; E2F2; MEIS1; IKZF1; GATA2
Down-regulation 185 CCNA2; NUP62; CRK; SUV39H1; PUF60; FHL2; LOXL2; TLE1; XBP1; CENPF; FOSL1; ECD; HOXA10; RNF4; USP22; SNW1; EED; ATF1; JARID2; DEK; HNRNPD; TRIM32; RBM14; MNT; DNAJC2; ADNP; CTR9; NPAT; PAX8; EZH2; MAGED1; SMARCE1; MED6; MED1; VEZF1; MAX; BLM; TP53; CBX3; CCNC; NCOA6; NFKBIA; NCOA4; SMARCA5; PHF20; UBE2I; TBP; ING2; BASP1; SCAND1; ZNF146; BAZ1B; ZNF266; REST; CDK7; RFC1; ITGB3BP; BCL10; CRY1; DDX5; EDF1; SUZ12; ZMIZ1; PLAGL2; NELFB; BRD3; WHSC1; ZMYM2; ZBTB1; ASXL1; BMI1; RREB1; RBBP4; CDYL; KAT7; KDM2A; PKNOX1; ATF4; PATZ1; ZBTB38; STAT5B; GTF2IRD1; TSC22D2; ARID4B; ERBB2; CARM1; TAF10; TCF20; SFPQ; RBBP7; AGO2; HDAC2; SIX1; PURA; NKX3-1; BRD8; CCDC59; BRCA1; RCOR1; CNOT1; ZBTB18; HMGB1; TAF9; SETD2; SOX4; SMAD2; FOXJ3; YWHAB; AFF1; ELK3; SF1; BCLAF1; CTBP1; HOXC6; NFKB1; ENO1; HMGB2; NAB1; TCF12; MBD2; MED13; TRIM29; ZNF410; REPIN1; PTTG1; HSBP1; ELF5; TFAM; RUNX1; PQBP1; CHD1; NR2F2; SETD3; E2F3; RAN; HLTF; MGA; KMT2A; IRF7; NPM1; TMF1; GATAD2A; DNAJC1; XRCC6; NRBF2; ZBTB11; HOXA5; FOSL2; CEBPZ; NFE2L1; PCGF2; NCOR2; PTRF; SUB1; TBL1X; STAT1; MAFB; SERTAD2; MNAT1; DNMT3B; PDLIM1; BHLHE40; BBX; TRIM16; HTATIP2; MITF; KLF6; ZNF131; HOXC10; FOXC1; VGLL4; FLNA; BTG1; IKBKAP; BIRC2; HMGN3; FOXD1; RBBP8; NFIB; KLF10; RXRA; FOXO1; TRIP6; SOX9; ABL1