Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID08060 Fostamatinib GSE70138 HA1E Human 24h 0.37uM EID0010
Types Number Response transcription factors
Up-regulation 13 ADRB2; NR1H2; MAFF; IRF1; MITF; BHLHE41; TXNIP; SMAD1; PBX1; ZNF91; KLF9; MAFB; SOX11
Down-regulation 24 ARID5B; TBL1XR1; CD3D; NR4A2; HDAC1; LMCD1; NFATC3; ZNF512B; ZBTB18; JARID2; SP100; IRF8; CREB3L2; KDM5D; HHEX; TOB1; THAP11; NR2F2; TBX3; SNAI2; ASCL1; ID1; WT1; TBX2