Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID08059 Fostamatinib GSE70138 HA1E Human 24h 1.11uM EID0010
Types Number Response transcription factors
Up-regulation 22 HOXA10; MYCL; BRD7; ELF4; SOX4; CRY1; ZNF32; INSR; BHLHE41; HOXC10; ZNF184; PIR; TFAP2C; HOXD1; ZBTB16; CTBP2; HOXC6; MYB; BACH2; TBL1X; HOXB6; ASCL1
Down-regulation 22 PRRX1; STAT1; FOSL1; YAP1; CITED2; KLF9; COPS2; ENO1; KLF2; ID1; WWTR1; IRF7; ZEB1; ZBTB38; RXRA; ZNF91; TGFB1; SNAI2; KDM5D; CREB1; TXNIP; TBX2