Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID08057 Fostamatinib GSE70138 HA1E Human 24h 10uM EID0010
Types Number Response transcription factors
Up-regulation 44 NFKBIA; CEBPD; DAXX; HDAC5; EPAS1; HBP1; MDM2; TCEA2; KLF3; PBX1; FOS; FOXE1; TCF7L1; SALL1; GTF2I; HIPK3; HOXA10; SOX4; MXD1; DLX5; JUP; MITF; TULP3; INSR; OSR2; SIX3; PIR; KLF11; SOX17; ZNF711; TRIM29; PAX6; ZHX2; ELF3; INSM1; TRIM22; ARNT2; ZFP36L1; ID1; PAX5; RBBP8; TOX3; NR2F2; EMX2
Down-regulation 26 MYC; HES1; CCNC; RORA; ENO1; FOSL1; RAN; RNF6; BHLHE40; ELK3; C1QBP; NPM1; YWHAB; SMAD7; SFPQ; MAGED1; SOX9; ZNF281; ZBTB38; ZBTB18; FLNA; BMI1; TOB1; CREB1; THAP11; TBX2