Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID08055 Gsk-1059615 GSE70138 HA1E Human 24h 0.12uM EID0010
Types Number Response transcription factors
Up-regulation 72 SSBP2; PPARG; BPTF; ESRRG; ARID5B; SMAD2; ZBTB1; THRA; ZNF107; SIX6; FOXI1; SMAD7; SOX4; JUP; VDR; PLAG1; ALX1; THAP10; SMARCB1; POU2AF1; PBXIP1; PPP1R13L; POU4F1; SMAD6; MAGED1; ELK3; GFI1; ELF5; TRIB3; HMGB2; BATF3; SMAD3; TGIF1; CNOT2; KDM5D; YEATS4; CREG1; MEOX2; HOXB7; CENPB; BATF; LPIN2; BRD8; RHOA; ZNF532; TFCP2; STAT5A; NFE2L3; EGR2; FLI1; PLAGL1; LMCD1; BCL3; ARNTL2; ELF3; TRIM29; RBBP4; TCF12; MED24; TWIST1; SATB1; STAT4; PAX5; HHEX; AEBP1; PITX1; ID3; ID4; BTG1; MEIS2; YBX3; CREB1
Down-regulation 52 CRK; TGIF2; ZNF665; ZNF593; ZNF93; ZNF654; UBP1; CCNH; MTDH; PBX2; PSMC3IP; TFDP1; HOXD1; ZNF160; JUN; CEBPB; HMBOX1; TFDP2; FOSB; ASCL1; NR2F2; BNC2; WT1; ESR1; ZKSCAN1; ZNF611; WWC1; SCAND1; COPS5; SFPQ; FOSL2; ETS1; ZNF721; NR4A2; TSC22D2; ARNT2; NFATC3; SIM2; CARHSP1; MXI1; CTBP2; MTF2; MITF; KAT6B; FOXC1; MYBL1; MSX1; HMGN3; CITED2; AHR; TBX3; THAP11