Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID08054 Gsk-1059615 GSE70138 HA1E Human 24h 0.37uM EID0010
Types Number Response transcription factors
Up-regulation 97 GLI2; TCEA2; HLX; ELF2; NFIL3; EZH1; ZNF212; ZNF589; KAT6A; PPARD; MDM4; STAT2; EZH2; MEOX2; ZNF692; HDAC6; MEN1; MAGED1; SETDB1; RBPJ; SOX4; ARID5B; ZFP36L2; MZF1; MED24; ZNF536; SOX9; SP2; NR1H3; HOXA10; TFEB; NR2E1; ELF3; LZTR1; CALCOCO1; POU2AF1; CBX7; TFEC; KDM5D; ZKSCAN7; NR2F1; ZNF146; IRF8; BACH1; GRHL2; RHOA; HIRA; SIX3; ZNF282; ZNF571; MNDA; TSC22D1; SSX1; MSC; HDAC7; AR; IRF9; TEAD3; SIX2; IRF6; PIAS1; TBX2; BCL6; TRIM22; TLE4; HOXC10; RBPMS; PLAGL1; ZBED1; ZNF22; CARHSP1; TCF21; TCF7L1; CD3D; ZKSCAN1; ST18; EGR2; SOX11; CUX2; MYRF; TRIP6; CUX1; HOXA11; ARID1A; IKBKAP; TCF4; BHLHE41; ZNF83; SMAD7; MYB; KLF9; HLF; CRYM; FOXC1; FOXG1; OSR2; ABL1
Down-regulation 60 CNBP; PAX8; HNRNPD; FOSB; BRD2; IRX5; TFDP1; SOX17; CENPF; CCNH; USP22; ZNF148; YWHAB; TGIF2; SFPQ; TAF10; EDF1; KLF2; RAN; COPS5; CCNE1; CCNC; TBPL1; E2F3; HSBP1; BRD4; ETS1; NR4A2; DNMT3B; ZBTB38; MXI1; TFDP2; BIRC2; ZMYND8; RFX5; NR2F6; FOS; PTTG1; ZFP36L1; ID1; HMGN3; ESR1; TRIM24; CHD7; KAT6B; THAP11; CITED2; TOB1; BTG1; KLF4; HHEX; ZHX2; MECOM; RBBP8; ATF3; DACH1; CREB1; MSX1; CEBPA; GATA2