Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID07933	Alectinib	GSE70138	CD34	Human	24h	10uM	EID0111

Response Information :

Types	Number	Response transcription factors
Up-regulation	69	MTF2; HES1; NFKBIA; RELB; MBD2; BTF3; SMAD4; SUMO1; SP100; SP110; NR0B1; CCNC; GTF2A2; KLF10; C1QBP; IRF2; BHLHE40; SP140L; PMS1; PNRC1; NFKB1; PREB; MTDH; ZBTB16; CITED2; MEOX1; STAT1; ZNF467; SATB2; RNF10; MYC; BATF3; CREB1; TSC22D1; NCOA4; BAZ1B; ST18; BBX; BTG1; HOXD1; NR1H3; HLX; BCL6; ARNTL2; KLF11; RBBP8; JAK2; SOX10; SREBF1; IRF1; IFI16; MYRF; FOXO1; ZEB2; SNAI2; HDAC9; TDP2; BAZ1A; MECOM; ZMIZ1; KLF9; BHLHE41; KLF2; ZHX2; IRF4; IRF9; ZNF281; ATF5; PSIP1
Down-regulation	84	RB1; FOXM1; EYA2; ELF5; CIITA; NELFB; PHOX2B; ADRB2; RNF141; SOX9; TADA3; NR2F1; NFRKB; MAF; ZNF83; KDM5D; ZNF573; AEBP1; SSRP1; CREB3L1; ZNF226; INSR; PUF60; CIZ1; ZNF443; PCGF2; SREBF2; SAP18; KLF5; ZNF91; ZNF544; TBL1X; PFDN5; GLI3; HOXC10; ZNF426; TAF9B; TRIM29; ZFP36L2; ZBED1; ZNF136; ZNF117; FOXD1; HOXC6; ZFP36L1; PHF1; IRX4; RBBP5; EGR1; CTBP2; TSC22D2; ZIC3; ZNF329; KLF6; IRF6; FOXE1; CAMTA1; LIN28A; ETV5; ZNF266; LEF1; CEBPD; CBX7; ZNF468; RUNX3; TGFB1I1; TP63; ZNF331; ZBTB38; RBPMS; RFX5; HMGN3; VGLL4; RORA; PTTG1; MYBL2; TXNIP; TRIB3; DACH1; MEIS1; MYBL1; SUV39H1; ZNF131; NFATC3