Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID07910	Vx-745	GSE70138	CD34	Human	24h	3.33uM	EID0111

Response Information :

Types	Number	Response transcription factors
Up-regulation	62	RB1; DR1; MBD2; GTF2A2; NRBF2; MLXIP; RNF10; FOXC1; RHOA; SMAD4; CHD7; TBP; FLI1; NEDD8; NFIB; C1D; CCNC; SMARCD3; SMAD2; CBFB; VEZF1; RNF138; CREB3L2; HMGB1; NCOA4; TCF12; YBX1; ELF1; HHEX; CTR9; PPARGC1A; MYC; NFKBIA; CRY1; RCOR1; HTATIP2; TAF10; TRIM22; HLTF; ZNF516; YWHAB; LEF1; KLF9; MYCN; KLF6; CCNE1; PSIP1; SAP30; WWTR1; RFX5; TAL1; ZMIZ1; NFATC3; NR2F2; KDM5D; TOB1; MNDA; HMGB2; EGR3; CREG1; TXNIP; ID3
Down-regulation	106	NANOG; PBX2; ZNF688; POU5F1B; TEAD4; TCEA2; ZNF10; MED24; FOXM1; ZNF91; SSBP3; SOX21; LIN28A; CNOT3; TRIM16; NAB2; CREBL2; BRWD1; ZBTB17; PHF1; LHX3; EPAS1; ZNF189; ZNF257; CRYM; ARNT2; SNAPC4; ZNF141; CAMTA2; HMGA1; ZNF606; TOX3; ZKSCAN7; ZNF593; MED15; MED16; ZNF136; DAXX; ZNF232; EHMT2; FHL5; KLF5; ZNF254; LOXL2; PRRX1; CTNNB1; LITAF; RBPMS; PLAG1; CAMTA1; TGFB1I1; SOX9; TWIST1; NEUROD1; ZNF512B; TFDP2; IRX4; EYA1; ZNF430; CREB3L1; ZNF544; ZNF423; STAT4; SOX13; INSM1; TCF7; MYT1L; POU2AF1; NR4A1; NHLH2; TRIB3; ZNF117; TFAP2C; YAP1; HOXD3; RERE; CBX7; CALR; JUNB; ZNF160; TBL1X; ZBTB20; IRF6; PBX1; PEG3; HDAC9; MYRF; MAGED1; HIRA; TFEC; BNC2; NFATC4; HLF; ESR1; SMAD1; TCF4; TP63; HEY1; BHLHE41; ZNF331; SOX11; ID4; MEIS2; BASP1; ZNF586; SMAD3