Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID07903	Dabrafenib	GSE70138	CD34	Human	24h	10uM	EID0111

Response Information :

Types	Number	Response transcription factors
Up-regulation	153	NR3C1; HES1; LHX6; PAWR; ZNF652; ZNF721; UBE3A; RARA; SUV39H1; PIAS1; PQBP1; TRIM33; ZNF611; TSC22D2; AGO2; TFCP2L1; TBL1XR1; NCOA1; NFKB1; RSF1; ZNF44; SRCAP; HSBP1; CDX1; WWP1; BPTF; DACH1; BANP; RNF111; FOXF1; BCL10; CRYM; EYA1; PBRM1; NR1I2; TRIP6; CDC5L; ORC2; ZNF654; TMF1; CREB3; ZNF224; REXO4; HIVEP2; KLF9; ARID3B; NFX1; NR1H2; MECP2; STAT2; ZNF217; TCF12; TSC22D1; ZMYND11; SATB2; CREBZF; HIPK1; RXRG; CHD9; KDM4A; SUPT3H; TCF7; L3MBTL1; PSPC1; NCOR2; RREB1; ETS2; SIRT7; ZNF160; DNAJC1; KMT2A; BAZ2B; TOX3; ATF7IP; CDX2; ELF5; MEIS1; TCEB2; MED23; DDX17; NCOA2; CDYL; ZNF165; KLF4; PHF20; ZNF143; LEF1; MTDH; NCOA6; CREM; MKL2; SOHLH2; KAT6A; MED13; PEX2; JARID2; ZMYM2; NR3C2; EDF1; HOXB13; JUNB; ZNF136; MYC; MYCN; REL; LITAF; BRIP1; ZFHX3; MBD2; ZNF264; ZEB2; NR4A1; DDX5; ZHX2; PHIP; ZFHX4; IRF2; MTF1; VEZF1; DEK; TFEC; SMAD4; KAT2B; IRF1; SSX1; FOXA1; ATN1; VDR; BMI1; SALL1; CREB3L2; REPIN1; CRY1; CALR; KLF5; BTG1; KLF10; ARID4B; PBX3; NFE2; RYBP; CUX1; NFATC3; MECOM; IRF4; BASP1; AHR; RAD21; ZNF512B; HEY1; TCF4; ID3; KDM5D
Down-regulation	137	RUVBL1; HMGA1; NR2F6; C1QBP; PSMC3IP; NFIB; NR2F1; CNBP; CREB3L1; KLF12; YBX3; ZNF593; NFE2L3; RORA; HOXD9; POLR3F; E2F6; NONO; ZNF155; ZKSCAN5; HOXA11; EYA2; GCFC2; FOXO1; SOX9; TRAK1; ERCC2; ARNTL2; ZNF195; KLF11; CEBPG; ZNF232; SATB1; ZNF614; ZNF133; TRIM28; MED27; MYT1; NANOG; ZNF79; SKI; HOXB6; KLF7; ZNF415; CBFA2T2; GLI3; CITED2; ZNF132; USP21; FOS; MTA1; SIM1; APEX1; MYRF; LPIN2; TRIM22; PEG3; ZBTB18; HOXD10; DEAF1; ZEB1; VAX2; POU2AF1; SMAD7; SUB1; INSR; ZNF239; SP140; ZBED1; TEAD4; GATA4; BIRC2; RBBP8; ADRB2; POU4F1; TXNIP; ZBTB16; HOXA1; CBX6; WT1; NR0B1; CERS4; TEAD3; PTRF; THAP10; ING2; SMARCD3; TGIF2; PCGF2; NR0B2; NFE2L2; BBX; SIM2; PTTG1; YEATS4; SMAD1; ZNF43; PAX5; TGFB1; RERE; ZNF268; ANKRD1; TBL1X; ZNF177; BACH2; ZNF432; CENPF; ZFP69B; TGFB1I1; ZNF85; HOXD3; IRF7; FOXC1; ZFPM2; CBFB; RBPMS; EGR2; ZNF423; ZNF304; BNC2; SHOX2; GATA6; SOX11; SMARCA1; ETV5; ZNF532; HOXB7; RBPJ; IFI16; ZMIZ1; HOXC6; ATF3; ZNF281; PIR; MEIS2; PSIP1; ZNF586