Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID07712	Alectinib	GSE70138	CD34	Human	24h	0.04uM	EID0110

Response Information :

Types	Number	Response transcription factors
Up-regulation	78	STAT1; E2F8; E2F6; NFE2L3; ZEB1; KLF7; TCF7L2; CCNE1; HOXB2; MEOX1; MEIS2; TTF2; RBBP8; YEATS2; EGR2; MECOM; MED17; BRIP1; ERBB4; PEX2; SHOX2; VPS72; TFAP2C; TRIB3; TFAP2A; WWTR1; FOXC1; NR2F1; ELF5; ID1; ZFHX4; SMAD7; RBFOX2; TWIST1; CITED1; ZNF131; PAX6; TAF7; ILF2; MYCN; ETV5; TLE2; SUB1; ARNTL2; IRF9; BACH1; DLX2; HOXD1; NKX2-1; CREB1; HOXB6; TLE4; TRIM22; HHEX; NFATC4; SMAD4; CITED2; EN1; TDP2; ISL1; E2F5; HBP1; CUX1; ATF3; MYBL1; NPAS2; PBX1; ZNF232; ST18; TCEA1; FOXF2; ARNT2; HOXB7; TGFB1; FOXF1; LOXL2; ZMIZ1; CREG1
Down-regulation	63	ATF5; HMGB2; PTTG1; SSRP1; PATZ1; ZBTB18; SMARCD2; NKX3-1; RBBP5; TAF10; NR1H3; BATF; MITF; YBX1; CHD3; SMARCA2; CTR9; KLF1; NEDD8; RBM14; PHF20; SAP18; NR1I2; RLF; NFATC1; SREBF1; SIM2; SPIB; AFF1; AEBP1; HDAC6; TRIM28; NKX2-2; MAZ; POLR2A; STAT5A; IRF8; MYB; CTNNB1; ZMIZ2; BASP1; ING3; SCAND1; TRIM16; TXNIP; MAGED1; JUP; MAF; ENO1; ZBTB20; BCL11B; HOXC10; TOX3; HMGB3; TBX3; NFIB; HTATIP2; TBL1X; HOXC6; ADRB2; MAFB; KDM5D; PEG3