Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID07710	Alectinib	GSE70138	CD34	Human	24h	0.37uM	EID0110

Response Information :

Types	Number	Response transcription factors
Up-regulation	92	SP140; SCRT1; TFDP2; POU6F2; ZNF215; E4F1; CBX2; NEUROG2; SMAD1; TP73; SRY; VPS72; TFAP2A; BHLHE41; CEBPG; PSMC3; ELF3; KLF11; PRPF6; SOX18; POU4F1; CREB3; CCNE1; TRIB3; HDAC9; ANKRD1; PHOX2B; IRF6; WWC1; TCEA1; MEIS2; PRRX1; DLX5; ZBED2; NFATC4; ZEB1; MKL2; VGLL1; TGIF2; FOXE1; LMCD1; TWIST1; PAX5; ZHX2; ERBB4; ILF2; ZNF331; CREB1; ZFP36L2; ZFPM2; NCOA2; ZNF423; HIPK2; PBX1; BCL11A; PFDN5; TERF1; SSBP2; ATF4; FOXI1; MYBL1; EN1; ATN1; ID3; SOX13; POU2AF1; IFI16; HOXB6; ETV5; EHF; MYRF; SOX11; ZNF107; PAWR; TCF7L1; YBX3; SOX17; PTRF; ATF3; TP63; ARNT2; ST18; NKX2-1; INSR; HHEX; E2F5; NR2F6; GATA6; PEG3; ZSCAN18; SOX9; MECOM
Down-regulation	60	EWSR1; MAF; PLAGL1; DNMT3B; HMG20B; STAT1; SIAH2; MAZ; POLR2A; USF2; BAZ1A; WWTR1; EGR3; MITF; SLC2A4RG; TAF10; TBL1X; CHD3; TSC22D2; PBRM1; TCF25; TP53; GATAD2A; ZNF189; NFKB1; MED1; JARID2; HSBP1; TRIM28; BCL6; HMG20A; NCOR2; BMI1; NR2F2; CARHSP1; ZNF587; ZMYM2; HTATIP2; PIR; NUP62; HLTF; ZEB2; HOXC10; FOSB; RUNX3; BASP1; HMGB3; KLF2; LEF1; ZBTB20; CITED2; ZIC1; FLNA; HOXC6; MAFB; ZBTB38; TOX3; NFAT5; KDM5D; IKZF1