Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID07686	Vx-745	GSE70138	CD34	Human	24h	0.37uM	EID0110

Response Information :

Types	Number	Response transcription factors
Up-regulation	92	ZNF586; E2F2; PRMT2; HOXB9; CBFB; ZNF134; TCF7L2; DACH1; ERBB4; RARB; PLAGL1; EYA1; ZNF432; POU4F2; CHD9; ZFHX4; LZTS1; TFEC; NR3C2; ZNF124; ZBTB18; ISL1; E2F8; ZNF562; PROX1; YEATS4; ETS2; MEOX1; ESRRG; SMAD1; HOXB7; ZNF587; ZNF544; MYCN; HOXD3; ZNF467; NR5A2; NR2F1; ELK3; ARL2BP; ZNF302; LOXL2; IFI16; CCNC; POU2AF1; APEX1; KLF2; MSC; PHOX2B; CENPB; ZNF611; ZNF468; MBD2; TRIM22; BCL6; SUB1; TAF1D; HOXD1; TXNIP; HOXB6; ZFHX3; HIPK2; ZNF22; WWTR1; ZNF551; HLF; HMGN3; ERG; ZNF264; PPARGC1A; ZNF512B; SALL1; TCERG1; PRRX1; ID3; ZNF160; ZNF423; SAP30; NR2F6; GATA6; PAX5; ZBTB38; MAFB; BCL3; CREB1; MEIS2; NFAT5; KDM5D; BTG1; MNDA; TBX3; SNAI2
Down-regulation	54	HIPK1; CDK8; CDK2; DLX2; TFDP2; BRD4; RORA; YBX3; RREB1; ERBB2; MED6; VDR; RBBP5; PHF1; RNF6; MAFF; MKL2; SMARCA2; GRHL2; MAFG; NFE2; CTNNB1; GTF3A; WWC1; SMARCD3; PSIP1; DDIT3; NKX3-1; DNAJC1; BCL11B; UBE2B; ZNF281; SIAH2; ZMIZ1; ZBED2; ZFP36L2; HLTF; LITAF; PBX3; CD3D; ATF3; HTATIP2; BHLHE41; FOXF2; NR4A2; MYBL1; TFAP2C; ESR1; ID4; LEF1; PEG3; SMAD3; NR3C1; IKZF1