Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID07681	Dabrafenib	GSE70138	CD34	Human	24h	0.12uM	EID0110

Response Information :

Types	Number	Response transcription factors
Up-regulation	53	E2F2; FOXJ3; ZNF516; TRIM29; MAX; TSC22D1; NCOA1; NEDD8; FOXC1; HSBP1; TRIM24; ZNF267; SMARCA2; BMI1; ZNF443; GATA2; TCERG1; ZBTB11; BCLAF1; MSX1; KLF2; RREB1; RHOA; DDX5; FOXA2; TBL1X; AHR; C1QBP; POU4F1; NR2F2; ARID5B; ARID4B; BAZ1A; MED1; JARID2; JUN; PFDN5; CITED1; DNAJC1; TP63; PITX1; ELF1; MAFB; ZMIZ2; NR1D2; NFAT5; EYA2; MNDA; ZNF652; SATB2; PSIP1; LEF1; CREG1
Down-regulation	81	HSF1; CHD8; ID3; SALL2; TGS1; TGFB1I1; CDIP1; TCF21; TFDP2; HIPK3; BRD4; SOX11; CARHSP1; TERF1; TOPORS; ZNF22; MDM4; ERBB4; HIPK2; GLI3; LOXL2; SOX2; GTF2I; AEBP1; PBX3; SMAD6; ZFPM2; FOXM1; SOHLH2; ZNF711; TGFB1; NFYB; FOS; TCF7L1; ZFP36L2; KDM5A; LIN28A; HMGB1; ARNT2; ZNF557; POU2AF1; EPAS1; ZFP36L1; GMNN; ZNF304; PAX5; HOXC10; SMARCA1; ZFHX4; HIC2; ZNF281; TEAD4; RAD21; PTRF; FOXN3; ZNF239; NKX2-1; MEIS2; EN1; ETS1; TWIST1; FOXD1; JUNB; ZNF423; PAWR; NKX3-1; INSR; MYBL1; ZNF331; ZNF589; MECOM; SNAI2; MAGED1; CITED2; TFAP2A; ZNF91; HOXD1; MYRF; SMAD3; ID4; NFATC3