Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID07679	Dabrafenib	GSE70138	CD34	Human	24h	1.11uM	EID0110

Response Information :

Types	Number	Response transcription factors
Up-regulation	75	PDLIM1; NPM1; MYT1L; ACTL6B; RELB; RAN; GATA3; YAF2; FLI1; PRDM4; DNAJC1; GTF2F1; COPS5; MBD4; BRF2; MYC; NR2C1; APEX1; RNF10; HOXC4; ASH2L; NFE2L3; RB1; RBBP4; IRF5; ZNF84; TAF1D; HOXC10; TRIM22; RREB1; CDC5L; KLF6; MLLT10; JAK2; ELF1; MAX; MYCN; CREB3L1; CCNH; BMI1; DDX5; POU4F1; TFEC; FOXC1; MED13; HOXC6; ZNF721; GTF2A2; MNDA; CREB5; ZFP36L2; TRPS1; SOX9; HSBP1; LMCD1; PCGF2; ELF5; KLF2; ZEB2; NCOR2; CRY1; LPIN2; MED1; PPARGC1A; JARID2; LITAF; ZMYM2; ZNF91; SALL1; MTA1; BHLHE41; TSC22D1; TOX3; TXNIP; CREG1
Down-regulation	94	WWTR1; TCF21; ATF5; BRCA1; ZFP36L1; MYBL2; ZNF211; PLAGL2; CCNA2; TFAM; HMGXB4; PITX2; MEIS2; MEN1; CCNE1; ZNF134; ZNF473; HIC2; FOXF1; MYCL; TAF4; ATF7IP; ZBED1; HOXD11; TOPORS; CARM1; ZSCAN31; ZNF419; KLF10; ASXL1; HOXD1; MEIS1; NFYA; TEAD1; WT1; MED15; ZNF606; PRPF6; EYA1; ZNF304; FOS; CARHSP1; BRD4; ELF3; ADRB2; NR0B1; PSIP1; JUP; NKX3-1; NR4A1; HMBOX1; HOXD3; FOXM1; WHSC1; KLF13; EGR2; KLF5; HOXB2; PAX5; TRIM28; EHF; SMARCA1; KDM5A; ID3; SOX17; ETV5; TRIB3; ZNF232; ATF3; ZNF532; ERG; CREB1; YBX3; SOX11; NR4A2; ZNF331; FOXF2; CALR; AEBP1; FOSB; ZNF423; ZNF589; RBPMS; ZNF12; POU2AF1; NR2F1; TCF4; SMAD3; TFAP2A; TFAP2C; PBX3; SNAI2; MYBL1; NFATC3