Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID07678	Dabrafenib	GSE70138	CD34	Human	24h	3.33uM	EID0110

Response Information :

Types	Number	Response transcription factors
Up-regulation	116	MNAT1; ZNF131; BPTF; MTF2; ERG; TAF12; MYC; HMBOX1; DNMT3B; MED13; RB1; FOXO4; UBE3A; KLF6; ZBTB25; ATF3; RNF10; TSC22D4; PHIP; MED12; DDX5; MLLT10; ID1; SP2; JARID2; MLXIP; FOSL1; ZMYND8; KAT7; ARID3B; NRBF2; SF1; ATF4; SIX1; E2F3; ZBTB43; MXD1; DNAJC1; MAFG; TFE3; ARID3A; BRD3; BCL11B; DDIT3; RYBP; NCOA1; CTR9; AFF1; GATA2; CCNT1; RNF141; TFDP2; ZFHX4; CREM; MLXIPL; HDAC1; NEDD8; NR2C1; RBPJ; MED6; CHD9; NFATC3; ZNF10; KLF5; LZTS1; HNRNPD; KMT2A; BATF3; ID2; TBL1X; NFE2; CRY1; SERTAD2; ETS2; ZNF281; MEIS1; EP300; SIM2; MSX1; CUX1; IRF7; XBP1; ENO1; HOXB13; FOXJ3; NPAT; NR3C2; YWHAB; HTATIP2; EGR2; MED1; NCOR2; BTG1; PBX3; TCF12; EGR3; ZNF331; RFX5; SSX1; NR4A1; TSC22D1; NR4A2; ELK3; HLTF; NFAT5; MYCN; ZMIZ1; PUF60; LITAF; TRIM22; TRIB3; PSIP1; ABL1; HOXC6; CREG1; KDM5D
Down-regulation	93	NRIP1; BACH2; SUV39H1; SNAPC4; SPIB; PAX5; E2F8; THAP10; NCOA3; GTF2IRD1; ZNF593; EN1; NEUROD1; POU2AF1; MYBL2; ZNF146; PRPF6; CRYM; SP3; SOX15; SMARCB1; LHX2; THAP11; GTF3A; RARB; ZNF177; HOXD1; PCGF2; BCL11A; JUP; PTTG1; ZNF257; CDIP1; ARNT2; GATA4; TCEB2; BRCA1; PITX2; ZFP36L1; ZNF93; POLR3C; NR1H4; MYCL; THAP7; RNF14; FOXO1; ZNF253; RNF6; TGFB1I1; KLF7; ZNF124; GATA6; CARHSP1; EYA1; TGIF2; ERBB4; NFE2L2; WWTR1; CCNE1; FOXM1; HDAC9; PAX6; EHF; SPDEF; ZMYM2; SOX13; NR2F1; TCF7L2; MYRF; MYBL1; SMARCA1; ZBED2; ZNF43; PDLIM1; SOX9; ADRB2; SMAD6; SALL1; ZNF544; JUNB; HIC2; ST18; EYA2; FOXF1; MEIS2; SHOX2; ZFP36L2; ZIC1; FOXF2; SMAD3; ZSCAN18; TFAP2A; ZFPM2