Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID07481	Alectinib	GSE70138	CD34	Human	24h	10uM	EID0109

Response Information :

Types	Number	Response transcription factors
Up-regulation	93	TCF4; MEF2C; NFKBIA; MECP2; MAFF; UBE2B; NR4A3; CREB3; MED6; TSC22D1; BCL11A; FOSL2; NR0B1; SPIB; FOXI1; PIAS2; EYA1; TWIST1; SOX11; KLF2; ZNF536; HOXA1; AGO2; ZNF107; NFRKB; E2F6; MYC; E2F5; MKL2; HIC2; TAF1A; ZNF273; ZNF331; RNF6; TRIM16; NFKB1; PLAG1; SMARCA2; PNRC1; ISL1; NR4A1; FLI1; HMGN3; TCF7L2; ZNF354A; VDR; NCOA1; ZEB2; TULP4; SOX17; CHD7; JUNB; PLAGL2; FOXG1; OLIG2; HDAC9; EGR3; ZNF711; JAK2; TFAP2C; IRF4; ZNF202; MAGED1; NR4A2; JUN; GTF2A2; MED17; ATF3; KLF9; ETS2; FOSB; ZSCAN18; HOXD1; ZNF160; PAX5; TSC22D2; CREM; RELB; NKX3-1; TOB1; POU2AF1; RBBP8; KDM5D; EMX2; MYB; EGR2; CREB1; INSR; AEBP1; BHLHE41; ATF5; MEIS2; WT1
Down-regulation	71	HMG20B; MMS19; RB1; ZNF12; WWTR1; BRD8; HOXB5; ID4; PPARGC1A; HDAC1; EGR1; PTRF; TRIM27; SLC2A4RG; TULP3; SATB1; TLE2; DNMT3B; DBP; HLF; MXI1; TGFB1I1; NR2F2; HOXB6; VGLL4; CIZ1; KAT2B; TEAD4; ZNF211; FOXF2; NELFB; MED16; CD3D; CBFB; PRMT2; MED21; PROX1; SMAD6; YAP1; MAZ; TBL1X; MAF; TRIP6; MITF; ZSCAN31; INSM1; WWP1; EHF; ZBTB20; ENO1; TBX3; CERS4; NR2F1; SAP30; RBPMS; ADRB2; HOXB2; STAT6; TXNIP; ZFP36L1; NFIB; ID3; FOXF1; MAFB; PITX1; TOX3; ASCL1; TRIM22; PSIP1; MSX1; NFATC3