Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID07454	Dabrafenib	GSE70138	CD34	Human	24h	3.33uM	EID0109

Response Information :

Types	Number	Response transcription factors
Up-regulation	53	MAFF; RB1; RNF10; ZZZ3; LYL1; ZNF189; DDIT3; TCF7; SMAD4; TRIP4; MAFG; SMAD2; BCL11B; HAND1; HSBP1; EP300; ATF4; ARNTL; SREBF1; MLXIP; ZNF721; FLI1; MYT1L; ESRRG; ELK3; PLAGL1; BRD2; GATA6; CRY1; HLX; LPIN2; ZNF430; E2F3; CREM; CD3D; ZNF160; ZKSCAN1; FOXC1; MNDA; RORA; MEOX2; ENO1; ERG; TRIB3; TGIF1; PEG3; RUNX3; JARID2; ZMYM2; MAF; HHEX; ZIC1; EMX2
Down-regulation	57	MYBL2; ARID4B; UBE2I; MYBL1; BRCA1; CNOT3; SUV39H1; PSMC3IP; CAPN15; KLF13; FOXM1; TEAD4; TBX3; ZFP36L1; E2F5; FOXF2; GMNN; TCF4; TWIST1; CNOT2; NFE2L3; DLX5; PRRX1; ZBTB18; PBX2; NR4A1; HOXB6; CCNE1; SLC2A4RG; SUB1; CEBPD; CUX2; ZEB1; KAT2B; KLF5; ATF5; NFATC4; HMGN3; TOB1; ESR1; LOXL2; KAT6B; NR4A2; ARNT2; IRF8; TOX3; MECOM; NR1H2; TFAP2C; NKX2-1; ID3; PBX3; LEF1; NR2F1; PSIP1; ADRB2; NFATC3