Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID07233 Jq1-(+) GSE70138 CD34 Human 24h 0.12uM EID0075
Types Number Response transcription factors
Up-regulation 46 TOB1; FOXO3; STAT2; FOS; HOXA1; GATA2; GATAD2A; HOXB5; ZBTB18; TSC22D1; REL; BTG1; ZMYM2; PIR; BRD2; RBBP7; RUNX3; HOXB6; FOSB; CTBP2; SAP30; NFATC3; PRKDC; PAX6; ZNF264; PEX2; PDLIM1; ZNF652; MXI1; TXNIP; NFIB; NFE2L3; HOXA5; KLF5; TWIST1; NFAT5; DLX5; MYBL1; ATF3; CITED2; EGR1; BCL3; PSIP1; CREG1; NR4A2; PBX3
Down-regulation 73 SSBP2; NPM1; SOX11; TEAD4; SMAD7; IFI16; ZNF354A; PCBD1; ADNP; UBP1; NCOA3; PTTG1; TRAK1; CNOT6; CAPN15; SSRP1; KLF11; DEAF1; ZMIZ1; HDAC2; TCF21; FOXA1; FOSL1; PEG3; SUB1; RAN; GTF2IRD1; NFKB1; TLE2; AEBP1; DMTF1; TCF4; LIN28A; PITX1; ISL1; CBX6; PBX1; SIX1; MLXIP; KDM5D; YWHAB; TGFB1I1; ZNF239; ST18; HMGA1; POU2AF1; TBX3; NPAS2; ID4; ZFP36L1; PTRF; EGR2; ETV1; NR2F1; WWC1; YBX3; SPDEF; KAT6B; SOX10; INSM1; SOX13; TLE4; CITED1; AHR; CREB1; MDM2; ZNF589; WT1; ZNF423; LEF1; TFAP2A; SNAI2; ZNF131