Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID07206 Cgp-60474 GSE70138 CD34 Human 24h 0.04uM EID0075
Types Number Response transcription factors
Up-regulation 713 MNAT1; NFKB2; HMGA2; REL; ZIM2; BHLHE40; NFKBIB; BACH2; PRDM1; TFDP1; GLI2; ERBB4; PNRC1; MECP2; SCAI; OVOL1; ZNF354A; TAF4B; ZNF573; VGLL1; BCL11A; TDRD3; TCF7L2; E2F5; FUBP1; PAXBP1; ZFP30; CREB3L2; TFDP3; FHL2; SOX11; GATA4; ZKSCAN1; MZF1; ZNF286A; ZFP2; L3MBTL1; TSC22D3; LHX2; ZNF250; SIX3; ZNF345; FOXA2; NCOA2; ZNF177; FOXI1; GRHL2; E2F8; RARG; ZNF667; ZNF778; SNAI2; CDX1; TCF21; PAX5; SOX21; ZNF695; ZNF665; PRDM10; FOXL2; NR4A3; ZNF264; MED17; ASCL3; CUX1; NR2E1; CIITA; HOXB9; ZNF426; NEUROD2; ZNF165; ZNF816; POU6F2; ETV3; LHX3; ZNF74; MYNN; PRDM9; LMX1B; NR5A2; ZNF215; ESRRG; ZNF154; SP4; POU6F1; ZNF350; TGIF2; HOXD11; YEATS2; CUX2; MEN1; MAML1; SOHLH2; FOXE1; LHX6; ZNF331; CDIP1; ZKSCAN4; ID1; TBX19; RXRG; ZNF814; ZNF423; ZNF91; SOX14; TAF1C; LZTS1; YY1; KLF8; NFYA; ZNF343; ID3; NKRF; TTF1; TGIF1; TULP2; EMX1; NOCT; CARF; ZNF529; GABPB1; MEIS2; NRL; ZSCAN9; ZNF75D; TBX6; SUPT3H; ASH1L; ZNF223; DLX2; RSF1; FEZF2; WHSC1L1; TBX2; CDK2; TULP4; THAP10; SOX2; ZNF93; ZNF273; NEUROD6; CBX4; PAX7; ZNF184; SNAI1; VENTX; SP140; TAF12; RORB; RFX1; ZNF135; CCNA2; ZNF235; TFCP2L1; IRF1; NPM1; ZBTB43; ZNF682; MAFF; CHD2; EBF2; ZBTB44; DLX5; ZIC4; HNF4A; AIRE; ARID3B; NHLH1; GRIP1; UIMC1; ZXDB; CREBZF; USP16; PROP1; ZNF550; POU3F4; TAF1; THRB; SUPT7L; PRRX1; HDAC5; PAX4; FOXE3; TBR1; FOXH1; LIN28A; HOXA1; POU4F2; ZNF415; ZNF442; IKZF2; DLX6; EN1; MXD3; POU3F2; TULP1; PAX6; FOXP3; PRDM16; PAX1; HESX1; KLF15; TSC22D1; PEG3; NEUROG2; TFAP2A; BARX2; TWIST1; KLF7; MEF2C; ZNF623; TAF6L; ZNF440; ZNF394; NKX3-2; PRDM14; GFI1; ZNF551; ZNF221; ZNF253; PAX3; HLX; SOX17; ING1; HES2; HSF1; KLF6; NKX2-5; ZNF304; HIF3A; TAF7L; MED31; LMO1; RFX3; TP73; RFX2; IKZF3; SSX7; ZNF142; HIC2; DCC; ZNF79; FOXL1; TEF; ZNF107; ADNP; MYBL2; MECOM; ZNF556; ETS1; HOXB8; ARL2BP; PRDM5; BRD2; WWC1; PRDM12; ZNF493; ZNF614; BRD7; CHD7; ZSCAN32; ZNF532; ZNF507; GCM2; ZNF674; HNF4G; AFF2; SSBP3; ZNF335; ALX4; CCNT1; TRIM25; ZNF500; TBX5; ZNF701; ST18; ZNF571; TBL1Y; DOT1L; NEUROG1; PRDM13; JUN; POU1F1; MXI1; ONECUT1; NR4A1; ZNF536; SKI; NR2F6; MEOX1; FOXF2; EPAS1; ZNF132; TTF2; SCRT1; MBD4; BHLHE41; FOXD1; ZNF80; ZNF16; FOXD3; VPS72; MYF5; MYCN; TBP; LBX1; THAP9; HEY2; KLF13; MAP3K10; TCEA2; MAPK8IP1; ZBTB3; ZNF41; HOXC5; ATF3; SKIL; HEYL; CDX4; ZKSCAN8; CBL; ARHGAP35; AFF4; ZNF467; ATF7; TSHZ2; ZNF391; HOXA6; ATF6B; BRWD1; ZNF211; POU3F3; HOXB1; RBPJL; ZIC3; ZNF586; RBL2; SUV39H2; HOXD12; ZNF669; YAP1; TRIM22; MYBL1; HIPK2; ZNF510; EP300; GBX2; TAF1A; MKL2; ZNF780B; URI1; ZXDC; FOXC2; IRF4; ZNF232; ZNF85; CCNC; NKX6-1; AFF3; ZNF770; BRDT; ZNF362; ZKSCAN3; TERF1; ZNF195; DLX4; GTF2A1; ZNF613; NR6A1; ELK4; ZNF654; ZNF471; EYA3; KLF9; ORC2; PPARA; ZNF10; ZNF492; ZNF652; TLE2; MAML3; HOXC8; TRPS1; ZNF117; PGR; ZIC1; ZNF549; ZNF239; NR2C2; CBX2; ZNF214; POU4F3; TCF3; CREM; CRX; YBX2; CASZ1; CBFA2T2; ZSCAN31; ZNF407; ZNF324; SOX18; NFIC; RFXAP; PPP1R13L; MYEF2; FOXC1; BNC1; SOX1; IRX4; ZNF7; ZMYND11; MAFK; IRX5; ZNF225; ATOH1; GMEB2; TULP3; ISL1; MAK; MTA2; TLX2; ZNF81; HNF1B; MSX2; DACH1; ZNF22; PKNOX2; GCM1; ZEB1; TGS1; NACA2; TBX1; PRDM2; ETS2; ZNF711; HOXA2; SOX3; HOXB5; ZNF12; SMAD5; NFE2L2; CDC5L; ARID5B; SRY; POU5F1B; CITED1; MBD1; ZFHX4; ZNF224; ZNF287; STAT2; ZNF771; ZBTB6; STAT4; NFX1; KMT5A; ZNF180; GCFC2; NHLH2; RARB; MXD1; GTF2I; HIRA; ZNF430; NR3C2; CIR1; ACTL6B; SCMH1; SMARCA1; SPDEF; ZNF749; PBX3; RNF14; BTAF1; ZNF236; ZNF552; ZNF157; GSC2; PPRC1; NEUROD4; CNOT6; NFATC4; SNAPC4; YAF2; SOX5; LOXL2; ZBTB39; ZNF136; ZNF234; ZBED2; ZSCAN2; WNT4; GLI1; KDM5C; ZNF710; VHL; FOXG1; MED12; SIX6; DMRT1; ASCL2; ZNF155; PLAG1; ESRRB; ENY2; ZNF675; TFDP2; PEX2; ITGB3BP; CAMTA1; MYF6; NKX2-8; TLX3; ZNF557; LEF1; TOPORS; MYOD1; ZKSCAN5; EGR1; POU2AF1; BNC2; KLF3; HBP1; PRMT2; ONECUT2; NFKBIA; PML; ZNF14; ZSCAN18; E2F2; ZNF480; ZNF227; HMBOX1; ZNF44; ZNF34; SIM1; TRAK1; RBFOX2; NR0B2; PIAS1; BRIP1; POU2F3; BCL6; ID4; MYRF; HOXA11; ZNF33B; ZNF589; JUP; IFNB1; KAT6B; ZNF174; MYT1L; KDM5B; IKZF5; BRCA2; ZNF141; ZNF254; TLE1; ZNF460; E4F1; CAMTA2; MLLT10; PHF1; POLR3C; PPARD; ZNF222; ALX1; FOXB1; HOXD3; RING1; HEY1; NKX2-1; SALL1; LHX1; NFIX; TAF9B; FOXF1; SATB2; MYCL; RBM39; NR1I3; MDM4; TEAD3; NCOA3; NR2C1; TAF1D; ZBTB1; FOXO3; PITX3; ZHX2; FLI1; CCNE1; IFI16; ZNF334; PROX1; POU4F1; IRF9; EGR4; NAB2; SMARCD3; SERTAD2; RORC; CNOT3; ZSCAN16; HIVEP2; ASCL1; TCF7L1; NANOG; TFAP2B; NR2F1; ZNF208; PHOX2B; WT1; IRF6; COPS2; AR; PBX1; MLLT1; WWTR1; RREB1; CCNH; STAT1; PDLIM1; SRF; MED14; CREB5; TCF4; ZBTB16; WWP1; ZFY; ZNF835; SIM2; CSDE1; NFYB; SOX13; SUMO1; WDHD1; TDP2; PMS1; KLF5; MLXIP; SALL2; ZNF528; NEUROD1; DBP; ZNF43; FOXJ1; ZNF200; RBBP8; YEATS4; TRIM24; CEBPD; KLF4; DMTF1; GTF2IRD1; GABPA; MTF2; OVOL2; ZNF512B; FOXO1; HDAC9; RYBP; ZFP69B; AGO2; OSR2; PTRF; EYA1; TOB1; COPS5; RORA; BACH1; RHOA; NCOA1; NKX2-2; LMCD1; EHMT2; BARX1; ILF2; BRD4; NR4A2; SMAD4; OLIG2; ARNT2; NR1H2; MAFB; GATA6; MYC; MEOX2; TRIM29; CERS4; TRIB3; ESR1; EMX2; ZFPM2; TP63; EYA2; ZNF217; C1QBP; CHD9; DAXX; MEIS1; PAWR; ELK3; SSX1; PITX1; JAK2; FOSB; KLF10; HHEX; TOX; YBX3
Down-regulation 188 XBP1; DRAP1; CEBPA; HMG20B; TBL1X; THAP11; MAF; ZNF672; ADRB2; HDAC1; PMF1; EWSR1; NUP62; CENPB; ENO1; SNW1; PA2G4; JUND; KAT5; XRCC6; PCGF2; RBM14; SUV39H1; SMARCE1; NEDD8; ATF4; NELFB; BASP1; PARP1; TADA3; MAGED1; UBP1; HDAC2; KAT7; PATZ1; PCBD1; PUF60; BAZ1B; AFF1; ATF7IP; ZBED1; JUNB; HNRNPD; HTATIP2; ZBTB20; SFPQ; FOXJ3; KDM5D; SP2; SMAD2; MAZ; NPAT; PQBP1; BIRC2; MITF; GATA2; WHSC1; REPIN1; SSRP1; ZBTB24; ACTL6A; DPF2; CARM1; TFE3; MLX; ATF1; TAF10; NFYC; GATAD2A; HDGF; SMAD1; TCF25; BRCA1; ECD; ZNF443; SCAND1; TRIM28; ZBTB18; HDAC7; ARID5A; SREBF1; KAT8; FOXO4; YBX1; SPEN; BCOR; MED16; CBX3; PIR; ZNF146; RNF4; FLNA; IRF3; SP110; USF2; MED24; SMARCD2; ZNF358; ZNF593; BRD8; ATF6; SIRT7; RUVBL2; USP22; NKX3-1; RUNX1; BRD3; STAT5A; TXNIP; PRKDC; RAN; ZEB2; DDX54; BCLAF1; HDAC6; BRPF1; RBPJ; BMI1; DDX5; RNF141; GTF3A; EDF1; TSC22D4; LPIN2; PTTG1; ZNF787; ZBTB7A; DEK; SF1; PHF20; ZBED4; ZMIZ2; MYB; CTBP2; ERCC2; BAZ2B; SREBF2; ARID4B; NRIP1; CTBP1; SMARCA2; NLK; IRF2; RBBP7; AIP; ELK1; ABL1; DEAF1; EZH2; HMGB2; ZNF274; UBE2I; NONO; NCOA4; HMGN3; JARID2; TCF15; AATF; HOXA10; RBPMS; ZNF32; VGLL4; ELF4; ZNF721; ARID1A; PPARGC1A; TGFB1I1; ZFP36L1; NFE2L1; ELF1; CTNNB1; ETV5; STAT6; NCOR2; TLE4; ZNF160; MNDA; YWHAB; CREB3L1; CALR; NR1H3; BAZ1A; AHR; HOXB7; NR2F2; MTA1; HOXC6; PSIP1