Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID07180 Mk-1775 GSE70138 CD34 Human 24h 0.12uM EID0075
Types Number Response transcription factors
Up-regulation 56 ADRB2; CHD1; ZBTB11; MBD2; EED; TCF12; SMAD2; CTNNB1; MITF; ING3; LEF1; CREB3L2; ZFP64; RBBP8; ZNF302; RNF138; ID2; ZNF189; RNF111; NCOA1; TSC22D1; NR2F2; SMAD4; TOB1; NPM1; SAP30; RB1; ADNP; RHOA; ELF1; CTR9; HTATIP2; BAZ1A; NCOA6; STAT6; ZNF516; TCF7L2; MYCBP; STAT1; MAGED1; BASP1; TOX; BCL6; ZNF12; ZEB2; SIAH2; NFAT5; BMI1; ZMIZ1; KDM5D; NRIP1; TLE4; CREG1; KLF2; SCAND1; PSIP1
Down-regulation 113 ZBED1; MYBL2; PCGF2; SSBP3; CREB3; RBPJ; SKIL; PRDM1; BRD4; TEAD4; CSDC2; TGFB1; SNAPC4; ARID5A; ZBTB48; ZNF268; HOXB13; TBX3; INSM1; SOX11; HOXC8; JUP; WNT4; TBX1; FOSB; OLIG2; GTF2I; NFE2L3; PPP1R13L; CNOT3; GATA1; VGLL1; GON4L; HSF1; SOX3; SOX18; HIC2; CIZ1; ZIC3; GATAD2A; GFI1B; ARNT2; ZNF331; CAMTA1; TXNIP; MYCL; CDK9; ZNF711; TCF21; NEUROD1; SATB2; SOX9; KLF3; SIX3; EMX2; VPS72; FOXF1; SALL1; BCL11A; PRDM14; TRIM29; UBTF; TFAP2A; BARX1; HOXB5; ZEB1; ZNF432; ZIC1; ZNF665; ZKSCAN8; ZNF239; ZNF544; SMARCB1; GTF2IRD1; NAB2; KLF4; NANOG; TCEA2; HMGA1; EPAS1; PAWR; SOX13; PSMC3; DACH1; MED24; EGR3; MDM2; CUX2; NR1H2; IRF6; ZNF91; SMAD1; IRF8; VDR; ZHX2; ERBB4; HOXC10; ZNF415; HEY1; PEG3; ZBED2; IFI16; EGR1; ZNF512B; EHF; TWIST1; NR2F1; MYRF; DAXX; NR4A2; MEIS2; NFATC3; PBX3