Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID07137 Rucaparib GSE70138 CD34 Human 24h 0.37uM EID0074
Types Number Response transcription factors
Up-regulation 40 CEBPZ; JUN; THRAP3; CHD4; KLF10; CBFA2T2; ZBED4; SOX12; YBX1; CARM1; FOXK2; GFI1B; TGFB1I1; SHOX2; CTR9; MEOX2; IRX4; DNMT3B; MED24; CTNNB1; GTF2IRD1; NR1H2; MDM4; SMARCA1; IRF7; ESRRG; AHR; ZIC1; RBBP8; ZFP36L2; ZNF423; TOX; SOX10; FOXF2; KLF6; SOX9; KDM5D; ZBTB16; PSIP1; MSX1
Down-regulation 67 PURA; MTDH; HLX; ATF5; RFX5; ELK4; LEF1; SMAD2; IRF2; RUNX1; ZNF302; DNAJC1; CREM; NR1H4; ZNF14; ERG; HHEX; EHF; PIR; TTF2; RBL2; TLE4; TOX3; FOXA1; SAP30; TFEC; ID2; MITF; ZNF552; MNDA; NPM1; RXRA; PBX1; SPDEF; ETS2; NR4A2; WT1; MLXIP; HEY2; NR0B1; ZNF107; HOXB6; CITED2; ZHX2; CTBP2; TSC22D2; TBX3; IRF8; ELF5; ESR1; JAK2; EMX2; ZKSCAN1; BTG1; TSC22D1; ZNF91; PBX3; SNAI2; HOXB7; MTF2; ZEB2; KLF2; TRIM29; SUV39H1; MEIS1; MAFB; GATA6