Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID07136 Rucaparib GSE70138 CD34 Human 24h 1.11uM EID0074
Types Number Response transcription factors
Up-regulation 44 MNAT1; BATF3; NCOR1; CHD3; HDAC4; MYB; SIX1; KLF11; CENPF; TRRAP; MLXIP; IRF5; NR2C1; STAT6; ISL1; RBPMS; YEATS2; RXRA; JARID2; TRIM28; ZBTB1; ELK3; LYL1; NR1H2; TCF12; HOXC6; SIAH2; TCF21; CDK8; BTG1; AFF1; FLNA; FOXD1; RUNX3; IRF8; ZMIZ1; SATB2; SCAND1; ZBTB38; KDM5D; BASP1; PSIP1; MECOM; ATF5
Down-regulation 98 TFAP2C; ARNT2; HOXD13; EN1; PQBP1; BNC1; SIX6; NR5A2; TBX1; SRY; ZNF224; TFAP2A; ZNF273; EHF; DLX5; ELF5; ZNF117; SOX10; FOXE1; TRIM24; TRIB3; DLX4; BCL6; TFDP1; MYBL1; ID4; ZNF623; PRRX1; SOX2; SP140; CERS4; TBX3; PSMC3; SNAI2; PGR; ATN1; ZNF665; CSDE1; NPAS2; SOX9; ENO1; TRPS1; LITAF; LOXL2; EPAS1; MEOX1; ATF3; NHLH2; FOXF2; ZNF217; CITED1; POU2AF1; KLF5; HOXD1; MYT1; CDK2; ZBTB18; RAD21; KLF9; NEUROD1; DLX2; ZNF136; GRHL2; ZFPM2; HOXB6; ZNF195; NKX2-1; ERBB4; NANOG; ZNF43; SOHLH2; IRF6; SMARCA1; TOB1; ZNF589; HHEX; TCF7L2; ZNF131; TRIM29; CALR; PAX5; ZFP36L2; EMX2; ZIC1; LEF1; BHLHE41; ZNF91; TWIST1; ZEB1; SUB1; CREB3L2; MAF; INSM1; ZNF652; NR4A2; TXNIP; ZBED2; NFATC3