Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID07126 Gsk-1059615 GSE70138 CD34 Human 24h 0.12uM EID0074
Types Number Response transcription factors
Up-regulation 58 MBD2; SMAD2; RNF138; IKBKAP; VPS72; SMAD4; NFKBIA; TRIB3; TFAP2A; TAF1D; HDAC4; E2F5; FOXO1; STAT2; MTDH; PNRC1; ETS1; RXRA; ZNF467; ENY2; TCFL5; ARID4B; KLF13; BACH2; PBX3; DLX2; SP110; CTBP1; TCEA1; MKL2; CCNC; CDYL; LOXL2; TDP2; POU4F1; SP140L; NR1H3; ARNT2; HEY1; RELB; TFAP2C; NPAS2; BTG1; MXI1; BCL11A; LITAF; ZMYM2; HOXD1; FOXF2; MYCL; PLAGL1; FOXG1; PUF60; POU2AF1; BASP1; DAXX; ID4; TLE4
Down-regulation 43 VGLL4; MED21; RNF141; ELF3; ZNF443; CBX5; ZNF468; ZNF426; MTA1; HCFC2; ZNF562; CREB3L1; ELK3; ZMIZ1; CRY1; ADRB2; ZNF415; KDM5D; FOXM1; MLXIP; WT1; SOX9; CTR9; ZNF329; KDM5A; NKX2-2; FOSL2; RBPMS; ZBTB38; SALL1; PITX1; ZNF91; PEG3; CREB1; HOXB7; EGR3; LEF1; TOX3; MSX1; MAF; MYRF; HOXC6; SUV39H1