Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID07073 Gsk-j4 GSE70138 CD34 Human 24h 0.12uM EID0074
Types Number Response transcription factors
Up-regulation 125 MEF2C; NR1H4; JUN; MYBL1; EMX2; TULP3; ELK4; NFYA; WWC1; TFAP2A; NUP62; MEIS2; SOX5; TCEA2; FOXN3; THAP7; SOX18; USP21; BNC2; ZNF623; ZNF444; ZNF770; SOX12; ZNF512B; FOXK2; FEZF2; LHX2; TCF4; CREM; SALL2; ERBB4; ZNF331; CBX7; COPS2; CNOT6; ETS1; ZNF264; TRIB3; CNOT3; ESR1; MED21; ZNF557; ZNF239; SLC2A4RG; TRPS1; ZHX2; TGFB1I1; HLF; ILF2; CREBL2; ZSCAN31; ATF2; SOX10; NCOA2; TRIP6; WWTR1; ZNF589; NFATC4; BACH2; CTBP1; RBFOX2; IRF6; NR3C2; ZNF107; HDAC9; MKL2; AR; SP100; FOXE1; ZNF12; SOX11; RORA; ZKSCAN1; DAXX; ZBED2; MXI1; FOXG1; SHOX2; ZFPM2; RBBP8; PCGF2; BHLHE41; ZNF665; KLF11; TGFB1; ZNF415; NFIB; ZFP36L2; ZNF165; TFAP2C; LOXL2; CUX2; HIPK2; ARNT2; MECOM; HIRA; MED15; SALL1; HEY1; KLF10; POU2AF1; NR1H2; SOHLH2; HIC2; TWIST1; TDP2; WT1; TBL1XR1; ZEB1; AHR; ZNF33B; NANOG; ZNF532; PRRX1; BCL11A; IRF7; AEBP1; PBX3; SATB2; IFI16; ID4; HHEX; ZNF91; PSIP1; PEG3
Down-regulation 52 JARID2; HDAC1; RBBP7; HSBP1; HOXB7; ZBTB18; CARM1; PITX2; POLR2A; C1QBP; RHOA; DNAJC1; RNF141; BRD3; RNF6; MSX1; HMGB3; MYB; MAGED1; LEF1; BMI1; PDLIM1; XBP1; NEDD8; TBL1X; TOX3; NR2F2; HOXC6; CENPF; DDIT3; NRBF2; ENO1; MNDA; HOXB6; BCL11B; MAF; ELF3; CD3D; ZNF281; EGR2; FOXA2; TRIM16; RUNX3; EGR3; EDF1; TLE4; MED1; KLF2; AFF1; KDM5D; GATA6; SUV39H1