Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID06996 Gsk-461364 GSE70138 CD34 Human 24h 10uM EID0074
Types Number Response transcription factors
Up-regulation 154 TSC22D3; JUN; NFKB2; BHLHE40; ATF3; MAFF; TSC22D1; YBX3; NR4A3; EMX2; UBE2B; PAX8; BHLHE41; TBX2; PITX2; ZSCAN5A; NFKBIA; MED17; ZNF165; KLF6; ZNF589; RXRG; FOSL2; CREB3; FOXN3; E2F8; NFYB; PPP1R13L; GRHL2; TTF2; MSC; ZBTB43; SNAI2; TAF9; PBX3; TCEA1; HBP1; NFIL3; ARNTL2; TAF4B; PNRC1; MXI1; TULP3; ZZZ3; ZNF667; SP140; KLF13; RELA; SHOX2; SMAD4; TAF12; ZMIZ1; TFAP2A; SUPT7L; STAT1; PSMD9; ZBTB25; OSR2; DDIT3; ZHX2; SRY; HINFP; AGO2; ST18; TGIF1; ILF2; WWC1; EN1; ALX1; TAF1A; HIPK1; BACH1; TLX3; CDK2; HLX; POU2F3; ATN1; ATF4; TBX21; PAWR; BRIP1; TEAD3; CDK7; RSF1; LITAF; TRIM33; TFEC; TRAK1; HOXB6; ZNF770; EGR2; SP2; DR1; SALL1; HIVEP2; YEATS2; NR1H3; ETS2; CEBPG; BCL6; RELB; COPS5; EPAS1; ZIC1; IRF4; ZNF350; YEATS4; ARID5B; NCOA3; MYRF; CITED2; TRIB3; RORA; USP16; CREB3L2; ZNF141; NR5A2; CALCOCO1; ZBTB1; MEOX2; SUPT4H1; NFE2L1; HOXB2; NCOA2; E2F5; SOX3; ZNF232; PRDM1; FOXF2; SOX13; TRIM22; TCF7L2; NR1H2; MYCN; TCF4; NR4A1; TRIM29; ARNT2; DLX5; TDP2; TRIP6; SOHLH2; TWIST1; ZFP36L2; HOXB7; TOB1; CRYM; ZNF331; ZBED2; POU2AF1; ZBTB16; CREG1; GATA6; BTG1
Down-regulation 130 PARP1; MAF; RFX5; PA2G4; DRAP1; RUVBL1; ZNF302; ADRB2; HDAC1; PTTG1; TBL1X; RBM14; LYL1; NSD1; TRIM27; ABL1; ZNF721; RFXANK; NR2F2; TAF10; MYCBP; ESR1; ZNF32; ELK3; ZNF274; RBBP7; SFPQ; RNF141; PBX2; NR1I2; ZNF562; ZNF587; ZNF516; JARID2; HMGB1; ZNF443; HNRNPD; MAGED1; BRCA1; BRD8; SCAND1; CNOT1; SAFB; ZBTB20; SMARCD3; CBFB; SMARCE1; SMAD1; ZNF24; CTR9; TCF7; PITX1; MYB; IL16; ZNF580; MAZ; ZNF3; ZBTB18; VGLL4; UBP1; CHD3; SSRP1; MTA1; SATB2; ZBTB38; TOX3; TLE2; ZMYND8; TADA3; ERG; JUP; HMGB2; ZNF14; ZNF83; CALR; PSIP1; HSBP1; CENPF; KDM5A; MXD4; SMARCA2; MNDA; MAFB; TRIM28; ZNF160; NFYC; RB1; BAZ2B; KAT2B; DEAF1; ZNF329; XBP1; SMARCB1; RBPMS; NFAT5; EHMT2; WWTR1; CBX5; TCEB2; FOXA1; RUVBL2; HLF; ZNF593; TCF25; HHEX; BAZ1A; C1QBP; NR3C2; MYCL; BMI1; SUV39H1; NFIB; SOX9; CHD1; TLE4; DACH1; SMARCD2; TOX; HEY1; WT1; EGR3; TXNIP; DNMT3B; NR4A2; KAT6B; ASCL1; SSBP2; MSX1; NR2F1; FOS