Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID06990	Mk-1775	GSE70138	CD34	Human	24h	10uM	EID0074

Response Information :

Types	Number	Response transcription factors
Up-regulation	136	ZNF131; ADRB2; TSC22D3; SOX17; SCAI; CERS6; HDAC4; ZNF493; MYCN; WDHD1; KLF10; WT1; L3MBTL1; HESX1; FOXO4; ZNF286A; ID1; CREM; BCL11B; MYT1L; HIVEP1; KLF13; TOPORS; PEX2; PAWR; VPS72; ZBTB7A; MAML1; GRHL2; PURA; TOB1; PNRC1; ZNF217; TEAD4; HBP1; SMARCA1; MAFG; CUX2; CALCOCO1; BPTF; SMAD7; NANOG; ZSCAN31; SRY; CBX7; ZNF770; HOXD11; TULP4; RREB1; ZMYM2; ZNF423; ESR1; LMCD1; TOX; COPS2; LDB1; HOXB6; LHX1; CREBL2; TEAD3; ZNF141; SNAI2; ZNF12; SMAD6; TCEB2; ZNF516; TGFB1I1; NCOR2; BACH1; SOHLH2; EMX2; SOX3; TRIB3; SUB1; ZNF711; SKIL; CRY1; SMAD4; PITX2; NFATC4; KAT2B; ZIC1; MXI1; HMBOX1; TAL1; ZNF281; NFE2L1; TCF12; EYA2; PLAG1; FOXF2; MDM4; STAT1; PCGF2; HOXB2; IRF9; STAT4; MECOM; TCF21; PCGF3; TXNIP; MKL2; FOXG1; TDP2; ZNF589; MDM2; ZMIZ1; E2F8; CRYM; ZNF331; BNC2; SALL2; CUX1; LIN28A; KDM5D; ZIC3; ETS2; TFAP2C; KLF4; PSPC1; TRPS1; TWIST1; ZBTB38; ABL1; CD3D; ARNT2; PBX1; PRRX1; CREG1; HOXB7; OSR2; AEBP1; NRIP1; ZFP36L2; MEIS1; MSX1
Down-regulation	92	XBP1; CCNA2; BRCA1; RUVBL1; PARP1; EZH2; CBX3; C1QBP; XRCC6; PA2G4; FOXM1; CENPF; NPM1; CAPN15; CBX5; ZNF274; RUVBL2; APEX1; IL16; ARNTL; EWSR1; SCMH1; SSRP1; NFIB; HMGN3; HHEX; SIX2; GTF3A; THAP10; PTTG1; SMARCA2; TRAK1; IRF4; ELK3; CBFB; BCLAF1; MYCBP; HMGA1; HMGB1; MAGED1; HNRNPD; TRIM29; RAN; CEBPZ; ILF2; BACH2; PBX3; BATF; ENO1; SOX4; DNAJC2; ZEB2; ELF1; JUP; ELF3; KLF6; TRIM28; BLM; SP110; SOX10; RBPMS; KLF11; CITED1; TBL1X; MYB; CHD7; HMGB2; BHLHE41; TLE4; ZNF544; HIRA; SPIB; FOSB; CREB3L2; MNDA; TCF4; SMAD1; ELF5; SUV39H1; TBX3; CALR; KLF2; CREB1; HOXC6; NR1H2; ZBTB18; MTF2; FLNA; BAZ1A; PEG3; SMARCD2; POU2AF1