Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID06939 Gsk-1059615 GSE70138 CD34 Human 24h 0.37uM EID0073
Types Number Response transcription factors
Up-regulation 138 NFATC1; HDAC7; FOXO4; ASH2L; ERF; TCF15; APBB1; NR3C1; BTAF1; ARID4A; CDYL; NCOA2; HIVEP1; DDX17; ZNF217; LIMD1; SREBF1; PCGF3; ZNF281; HIPK1; PMS1; CENPB; WDHD1; ZFHX4; CALCOCO1; PBXIP1; BCL3; MLXIPL; DDX54; KDM4C; ETV4; TCF7; MAFG; ZFP36L2; DLX4; HIVEP2; TCEA1; ARID5A; SERTAD2; CHD1; SOX12; HOXB7; ZHX2; BRD3; TERF1; TOX; BAZ2B; IL16; FOSB; TFCP2; ZMYM2; TSC22D3; LMCD1; CEBPD; SMARCC2; LPIN2; E2F8; BASP1; ARID3B; E2F3; TSC22D4; PLAGL1; CBX7; NCOA1; TRIM22; ZNF652; ZNF532; ZNF224; NFATC4; PIAS1; TOB1; EGR3; E2F5; CREBL2; ZNF24; PSMC3; ZNF165; HOXB2; BRD2; VPS72; ELF3; BBX; NAB1; NFIB; MEIS1; NFYB; LOXL2; TP63; HOXC6; ZEB1; TFAP2C; COPS5; TSC22D2; WWC1; NPAS2; CALR; TGIF1; NFE2L3; MTA1; TCF7L2; FLI1; IRF4; IRF7; NONO; HOXB6; PAWR; DLX2; ZNF264; TRIM16; ID1; EN1; ATF3; SOX9; ZBTB20; KLF4; MYCN; CREM; WWTR1; MYBL1; HMGB3; SALL2; DACH1; PSIP1; RUNX3; HIC2; ZNF589; ELK3; SAP30; HOXA5; MYCL; SMARCA2; WT1; SMAD1; TRIB3; POU2AF1; CREG1; DAXX; ARNT2
Down-regulation 63 RRN3; TCEB2; KAT5; CLOCK; UBE2I; MXD1; HDAC2; RUVBL2; CNOT2; TXNIP; SKI; CHD8; ZNF274; ZBTB11; TRIM28; ZNF468; TAF7; ZNF528; MED7; PGR; MED21; ACTL6B; TMF1; NFKB1; FOXM1; GABPA; URI1; GTF2IRD1; TCF21; SALL1; FOXE1; YEATS4; MAGED1; MED24; AR; EGR2; FOXL2; MTDH; FOSL2; GATAD2A; MDM2; ZNF226; NKX2-2; PRRX1; ST18; TFEC; POU4F1; RBPMS; SUB1; PDLIM1; INSM1; BHLHE41; PUF60; CREB1; ESR1; TBX3; PEG3; MAFB; ZNF331; SMAD3; ZNF91; ZIC1; SUV39H1